Results 91 to 100 of about 13,959 (300)
FEBS Letters, EarlyView.Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani +3 more
wiley +1 more source
Low-density parity-check codes and their rateless relatives
, 2011 This survey guides the reader through the extensive open literature that is covering the family of low-density parity-check LDPC codes and their rateless relatives.
Sheng Chen +5 more
core +1 more source
Key Distribution System Based on Hadamard Designs
Моделирование и анализ информационных систем, 2019 The problem of key distribution in a community for providing secure communication between its participants is studied. To solve this problem, key predistribution systems can be used, in which each user receives some key information that can later be used
Vladimir M. Deundyak, Alexey A. Taran
doaj +1 more source
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
Uniform hypergraphs containing no grids
, 2013 A hypergraph is called an r×r grid if it is isomorphic to a pattern of r horizontal and r vertical lines, i.e.,a family of sets {A1, ..., Ar, B1, ..., Br} such that Ai∩Aj=Bi∩Bj=φ for 1 ...
Füredi, Zoltán, Ruszinkó, Miklós
core +1 more source
Finding combinatorial histone code by semi-supervised biclustering
BMC Genomics, 2012 Background Combinatorial histone modification is an important epigenetic mechanism for regulating chromatin state and gene expression. Given the rapid accumulation of genome-wide histone modification maps, there is a pressing need for computational ...
Teng Li, Tan Kai
doaj +1 more source
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Searching ChIP-seq genomic islands for combinatorial regulatory codes in mouse embryonic stem cells
BMC Genomics, 2011 Background To facilitate deciphering underlying transcriptional regulatory circuits in mouse embryonic stem (ES) cells, recent ChIP-seq data provided genome-wide binding locations of several key transcription factors (TFs); meanwhile, existing efforts ...
Chen Gong, Zhou Qing
doaj +1 more source
Combinatorial properties of codes with degree n
European Journal of Combinatorics, 2003 The authors study the very thin codes of degree \(n\). The combinatorial properties of synchronizing codes are extended to the codes of degree \(n\geq 2\). By using a very thin code of degree \(n\), it is shown that it is possible to localize the \(n\) positions of the coded message and that the decoding of the message must pass through one of these ...
Liang Zhang 0008 +2 more
openaire +2 more sources
Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers
Molecular Oncology, EarlyView.This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel +6 more
wiley +1 more source