Results 41 to 50 of about 2,665 (258)

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

Niat Adopsi Petani Dalam Menggunakan Teknologi Combine Harvester

Habitat, 2019
Kelangkaan tenaga kerja panen padi menyebabkan jadwal panen tertunda atau tidak tepat waktu. Keterlambatan panen dapat menyebabkan menurunnya kualitas maupun kuantitas hasil produksi.
Aulya Roudlotul Jannah, Hery Toiba, Novil Dedy Andriatmoko   +2 more
doaj   +1 more source

Lightweight Threshing Rack under Multisource Excitation Based on Modal Optimization Method

Advances in Materials Science and Engineering, 2020
Crawler rice combine harvester threshing rack excited by different frequencies of multiple working parts would cause strong vibration response. In this paper, the rack-type rice combine harvester threshing rack was taken as research objective, and then ...
Haotian Zhang, Zhong Tang, Yu Li, Xin Liu, Hui Ren   +4 more
doaj   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

FEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee, Junho Jeong, Chae Yeong Lee, Hyunjoon Cho, Man Hwan Oh, Je Chul Lee, Jee‐Young Lee, Yangmee Kim   +7 more
wiley   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

FEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi, João C. Encarnação, Valeria Napolitano, Grzegorz Dubin, Grzegorz Popowicz, Karl Andersson, U. Helena Danielson   +6 more
wiley   +1 more source

Modeling of a combine harvester speed for reducing harvesting loss of paddy

Discover Agriculture
Loss reduction of paddy during harvesting is one of the most strategic options for ensuring food security for the growing population of Bangladesh. Amongst the many other factors, harvesting speed of a paddy combine harvester is more crucial one to be ...
Sahabuddin Ahamed, Md. Jobaer Hossain, Md. Rostom Ali, Chayan Kumer Saha, Md. Mosharrof Hussain, Md Yeaqub Ali, Anisur Rahman, Md. Monjurul Alam   +7 more
doaj   +1 more source

Evaluation of Changes in Soil Compaction Due to the Passage of Combine Harvester

Acta Universitatis Agriculturae et Silviculturae Mendelianae Brunensis, 2016
This paper concerns the results of changes in soil compaction after the passages of combine harvester. The research was done on the maize-stubble; the soil was the mold formed in the sand.
Martin Svoboda, Marek Brennensthul, Jiří Pospíšil   +2 more
doaj   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

FEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang, Hyo Been Jin, Chang Min Kim, So Yeon Lee, Hyun Ho Park   +4 more
wiley   +1 more source