Results 111 to 120 of about 2,960,250 (255)

Efficacy of transrectal mpMRI / TRUS fusion-guided biopsy of the prostate: results of a study in 318 patients

Вестник урологии
Introduction. Prostate cancer remains one of the leading oncological diseases among men, necessitating precise diagnostic strategies. Contemporary approaches, including multiparametric MRI (mpMRI) with PI-RADS scoring and targeted biopsy, enhance ...
A. A. Izmailov, V. A. Vorobev, A. B. Chaprak, G. R. Akperov, T. H. Akchulpan, A. R. Khasiev, A. R. Farganov, A. G. Karimova, R. R. Khalimova, S. V. Sukhanova, Yu. N. Khrizman   +10 more
doaj   +1 more source

Characterizing Cutaneous α‐Synuclein Deposition and Seeding Activity in Parkinson's Disease Subtypes

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Cutaneous phosphorylated α‐synuclein (p‐syn) and α‐synuclein seeding activity are promising biomarkers for Parkinson's disease (PD), but their clinical value remains uncertain due to disease heterogeneity. This study evaluates these two biomarkers in PD patients to inform phenotype‐specific diagnosis and disease severity assessment ...
Yuting Jin, Tianyuan Yang, Minglei Liu, Haiyang Luo, Jing Yuan, Ke Zhang, Xinsheng Han, Jing Yang, Yuming Xu   +8 more
wiley   +1 more source

Biopsy interpretation of the thyroid Biopsy interpretation series./ Scott Boerner, Sylvia L. Asa.

, 2016
The normal thyroid -- The classification of thyroid pathology -- The cytologic approach to diagnosis of thyroid pathology : technical aspects -- The histologic biopsy of thyroid : technical aspects -- Ancillary tools in thyroid diagnosis -- Cystic ...
Boerner Scott L.,, Asa Sylvia L.,
core  

Re‐Purposing Sapropterin (Kuvan) for ACTA2‐Related Multisystemic Smooth Muscle Dysfunction Syndrome: A Translational Mechanistic and First‐In‐Human Therapeutic Report

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Multisystemic smooth muscle dysfunction syndrome (MSMDS) is an ultra‐rare, ACTA2‐related disorder characterized by severe cerebrovascular disease, aortic aneurysms, and smooth muscle dysfunction. Using molecular dynamics simulations and in silico drug screening, we identified that sapropterin dihydrochloride (Kuvan) is a candidate capable of ...
Moran Hausman‐Kedem, Noa Bielopolski, Vijai Krishnan, Shane Wald‐Altman, Shelly I Shrian, Omer Bar‐Yosef, Livia Kapusta, Claire Shamber, Patricia L. Musolino, Miguel Weil   +9 more
wiley   +1 more source

Development and validation of a predictive model based on clinical and MpMRI findings to reduce additional systematic prostate biopsy

Insights into Imaging
Objectives To develop and validate a predictive model based on clinical features and multiparametric magnetic resonance imaging (mpMRI) to reduce unnecessary systematic biopsies (SBs) in biopsy-naïve patients with suspected prostate cancer (PCa). Methods
Xueqing Cheng, Yuntian Chen, Jinshun Xu, Diming Cai, Zhenhua Liu, Hao Zeng, Jin Yao, Bin Song   +7 more
doaj   +1 more source

Autoimmune Comorbidities as Modifiers of Phenotypic Heterogeneity in Facioscapulohumeral Dystrophy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Facioscapulohumeral dystrophy type 1 (FSHD1) shows clinical heterogeneity that is only partly explained by D4Z4 repeat unit (RU) size. Although immune and inflammatory mechanisms may contribute to disease variability, the prevalence and clinical impact of autoimmune diseases in FSHD remain unclear.
Jonathan Pini, Giulia Tammam, Andra Ezaru, Manuela Gambella, Benoît Sanson, Luisa Villa, Michele Cavalli, Mihai‐Bogdan Ioncea, Angela Puma, Sabrina Sacconi   +9 more
wiley   +1 more source

COHQ bulletin Y/1 notes on the planning and assault phase of the Sicilian operation.

, 2003
The reports and observations of a military observer during Operation Husky.
Combined Operations Headquarters
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Precision prevention and cancer interception : the new challenges of liquid biopsy

, 2020
: Despite major therapeutic progress, most advanced solid tumors are still incurable. Cancer interception is the active way to combat cancer onset, and development of this approach within high-risk populations seems a logical first step.
Lorente, Jose A., Ruiz-Rodriguez, Antonio J., Carmen Garrido-Navas, Maria, Rolfo, Christian, Malapelle, Umberto, Cardona, Andres F., Pauwels, Patrick, Vilar, Eduardo, Gil-Bazo, Ignacio, Jose Serrano, Maria, Paz-Ares, Luis G., Raez, Luis E., Diaz Mochon, Juan Jose, Russo, Alessandro, Cristofanilli, Massimo   +14 more
core  

An appraisal of the histopathological assessment of liver fibrosis [PDF]

, 2006
One of the most important aspects of the histopathological assessment of liver biopsies in the setting of chronic liver disease is determination of the degree of fibrosis and architectural change.
Dhillon, A.P., Cholongitas, E., Dhillon, A., Burroughs, A.K., Standish, R.A.   +4 more
core  

Use of a hemostasis introducer sheath to guide clip delivery during stereotactic directional vacuum-assisted breast biopsy when the biopsy system malfunctions

, 2011
Stereotactic directional vacuum-assisted breast biopsy (ST DVAB) is an accurate biopsy method. Marking the biopsy site with a clip is mandatory after ST DVAB, in case excision is required.
王甄;張君如, WANG, JANE;CHANG, CHUN-JU   +1 more
core   +1 more source