Results 161 to 170 of about 16,510 (292)

Cyclic Treatment With WIN 18,446, a Potential Male Contraceptive, is as Effective as Continuous Treatment for Suppression of Spermatogenesis in Mice

Andrology, EarlyView.
ABSTRACT Background Retinoic acid plays a critical role in spermatogenesis during both spermatogonial differentiation and spermiation. Mice lacking enzymes that synthesize retinoic acid, Aldh1a1/1a2, in the testes are infertile. WIN 18,446 reversibly inhibits spermatogenesis by inhibiting ALDH1A1/1A2 and is a promising approach to male contraception ...
Jisun Paik, Jessica M. Snyder, Haley A. Martin, John K. Amory   +3 more
wiley   +1 more source

Perception about benefits and risks related to combined hormonal contraceptives use in women with Lynch syndrome. [PDF]

Ann Med
Barra F, Perrone U, Ferrero S, Bogliolo S, Ottonello S, Gustavino C, Iasci A, Grandi G, Pulliero A, Centurioni MG, Izzotti A.   +10 more
europepmc   +1 more source

Neoplastic Risk in Patients With Klinefelter Syndrome

Andrology, EarlyView.
ABSTRACT Background Besides gonadal involvement (hypogonadism, male factor infertility, and testicular hypotrophy), patients with Klinefelter syndrome (KS) may suffer from several extra‐gonadic complications, including neoplastic events. Objective The aim of this review is to summarize all major clinical evidence dealing with the association between KS
Andrea Graziani, Giuseppe Grande, Riccardo Selice, Antonella Di Mambro, Alberto Ferlin   +4 more
wiley   +1 more source

Clinically Significant Infections in Surgical Mortality

ANZ Journal of Surgery, EarlyView.
ABSTRACT Introduction Clinically significant infections (CSIs) are a common complication identified in cases of surgical mortality, associated with prolonged hospital stays, unplanned escalation of care and increased risk of death. This study aimed to examine the burden of CSIs in surgical deaths in the Australian Capital Territory and identify ...
Emily‐Rose Lodge, Helena S. Kopunic, Nathan E. K. Procter, Sivakumar Gananadha   +3 more
wiley   +1 more source

A practice tool for initiating and managing combined hormonal contraceptives for contraception: Assessment, decision-making and monitoring. [PDF]

Can Pharm J (Ott)
Yuksel N, Whelan AM.
europepmc   +1 more source

Use of combined hormonal contraceptives among women with migraines and risk of ischemic stroke. [PDF]

Am J Obstet Gynecol, 2017
Champaloux SW, Tepper NK, Monsour M, Curtis KM, Whiteman MK, Marchbanks PA, Jamieson DJ.   +6 more
europepmc   +1 more source

Risks of gynecological and breast cancers in women with endometriosis or adenomyosis: A nationwide cohort study

Acta Obstetricia et Gynecologica Scandinavica, EarlyView.
Endometriosis (including adenomyosis) is an inflammatory disease with lesions of endometrial tissue outside the uterus or in the uterine wall. In this study on Swedish women, endometriosis or adenomyosis was associated with persistently increased risks of breast and epithelial ovarian cancers, especially clear cell, endometrioid, and low‐grade serous ...
Louise Moberg, Xinjun Li, Filip Herbst, Filip Jansåker, Arturas Dobilas, Kristina Sundquist, Christer Borgfeldt   +6 more
wiley   +1 more source

Menopausal hormone therapy after ovarian cancer: A 10‐year survival analysis in premenopausal women

Acta Obstetricia et Gynecologica Scandinavica, EarlyView.
Among premenopausal women surgically treated for ovarian cancer, no difference in 10‐year overall survival was observed between postoperative MHT users and non‐users. Young ovarian cancer survivors should be recommended MHT after surgically induced menopause.
Åsa Ehlin von Kartaschew, Pernilla Dahm‐Kähler, Kenny Rodriguez Wallberg, Erik Holmberg, Angelique Flöter‐Rådestad   +4 more
wiley   +1 more source

Immediate placement of intrauterine device after second‐trimester medical abortion—Secondary outcomes with one‐year follow‐up

Acta Obstetricia et Gynecologica Scandinavica, EarlyView.
Immediate intrauterine device placement after second‐trimester medical abortion was associated with a higher incidence of expulsion, lower use of IUD at 12 months, and lower acceptance compared with delayed placement. However, no significant increase in subsequent pregnancies or abortions was observed at the 12 month follow‐up.
Sara Hogmark, Caroline Westermark, Niklas Envall, Kristina Gemzell‐Danielsson, Helena Kopp Kallner   +4 more
wiley   +1 more source

Combined Hormonal Contraceptive Usage in Women With COVID-19 [PDF]

International Journal of Women's Health and Reproduction Sciences, 2021
openaire   +2 more sources