Results 121 to 130 of about 666,236 (309)
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Zhongguo Jianchuan YanjiuObjectiveIn order to find a numerical simulation method that can simulate the combined effects of multi-damage loads under cabin internal explosion, while considering both simulation accuracy and efficiency, this paper proposes two high-efficiency ...
Zhenhao WU +2 more
doaj +1 more source
Flame radiation and liner heat transfer in a tubular-can combustor [PDF]
Heat transfer within a combuster were examined. Total and spectral flame radiation in a tubular can combustor at a series of parametric operating conditions was measured. Radiation measurements were taken for a range of inlet air pressures from 0.34 to 2.
Claus, R. W. +2 more
core +1 more source
COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
Molecular Oncology, EarlyView.This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source
Design Procedures for Fiber Composite Box Beams [PDF]
Step-by-step procedures are described which can be used for the preliminary design of fiber composite box beams subjected to combined loadings.
Chamis, Christos C., Murthy, Pappu L. N.
core +1 more source
Molecular Oncology, EarlyView.Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen +11 more
wiley +1 more source
Analysis of edge stress of combined shell under internal waves
AIP AdvancesInternal wave is essentially a gravity wave induced by the layered structure of water (e.g., density stable layering), with its maximum amplitude occurring within the ocean.
Yiqiong Cui
doaj +1 more source
Combined effects of thermal stress and ice impacts on polar ship hulls: A numerical study
Applied Ocean ResearchIn polar environments, the combined effects of low temperatures and ice loads greatly influence the structural response of ships. While existing studies have primarily focused on individual factors, systematic analysis of their combined effects is ...
Hegang Ji +5 more
doaj +1 more source
Buckling behavior of Rene 41 tubular panels for a hypersonic aircraft wing [PDF]
The buckling characteristics of Rene 41 tubular panels for a hypersonic aircraft wing were investigated. The panels were repeatedly tested for buckling characteristics using a hypersonic wing test structure and a universal tension/compression testing ...
Fields, R. A. +2 more
core +1 more source
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source