Results 221 to 230 of about 3,352,860 (301)

Directional dynamics reveal regimes of human visual examination. [PDF]

Sci Rep
Neves J, Jorge J, Moreira C.
europepmc   +1 more source

Hyperactive ice‐binding proteins stabilize cell membranes and improve resistance to dehydration stress in Caenorhabditis elegans

FEBS Open Bio, EarlyView.
TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose, Kotaro Ozaki, Ryohei Kuriyama, Yuka Ikemoto, Kazuhiro Mio, Yuji C. Sasaki, Tatsuya Arai, Sakae Tsuda, Yoichi Shinkai, Masahiro Kuramochi   +9 more
wiley   +1 more source

Differential associations of tau extent and load with brain metabolic and cognitive dysfunction in Alzheimer's disease. [PDF]

EBioMedicine
Macedo AC, Trudel L, Hosseini SA, Bezgin G, Quispialaya-Socualaya K, Therriault J, Rahmouni N, Tissot C, Woo MS, Limberger C, Machado LS, Souza DG, Oliva-Lopez D, Mitchell S, Chan T, Hall B, Aumont É, Servaes S, Gonçalves MP, Bernardes Real AP, Klostranec J, Vitali P, Provost K, Pascoal TA, Zimmer ER, Soucy JP, Rosa-Neto P, Alzheimer's Disease Neuroimaging Initiative.   +27 more
europepmc   +1 more source

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

FEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard, Emma‐Jayne Proctor, Jiawa Wang, Nikolas P. Johnston, Andrew Hayes, Georgia McCorkell, Haibo Yu, Jai Tree, Mark R. Davies, Mark J. Walker, Ronald Sluyter, Stephan Brouwer, Martina L. Sanderson‐Smith   +12 more
wiley   +1 more source

Contact Depth Affects Most of the Other Hitting Metrics We Analyze. [PDF]

Sports (Basel)
Giordano KA, Jump I, Lerch B, Oliver GD.
europepmc   +1 more source

Transcripts enriched in codons that trigger P‐site tRNA‐mediated mRNA decay possess stable mRNA

FEBS Open Bio, EarlyView.
PTMD codons were first described by Mendel et al. as mediators of an mRNA decay pathway dependent on the human protein CNOT3, homologous to yeast Not5. Our findings confirm that PTMD codons destabilize transcripts; however, unlike in yeast, the human pathway specifically targets and slightly destabilizes primarily stable mRNAs.
Rodolfo Lopes Carneiro, Fernando Lucas Palhano   +1 more
wiley   +1 more source

Frequency-Following Responses for Objective Neurophysiological Monitoring in Pediatric Fetal Alcohol Spectrum Disorder: A Proof of Concept Case Study During Non-Invasive Neuromodulation. [PDF]

Children (Basel)
Templado S, Medina-Ramirez R, Savio G, Almela MT, García-Purriños FJ.   +4 more
europepmc   +1 more source

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

FEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo, Sandy Richter, Christoph Bach, Wieland Kiess, Anna Kirstein, Diana Le Duc, Antje Garten   +6 more
wiley   +1 more source

Enhancing PET/CT Radiomics Robustness Through Graph Signal Processing. [PDF]

Diagnostics (Basel)
Latino T, Stefano A, Pasini G, Marinozzi F, Russo G, Bini F.   +5 more
europepmc   +1 more source