Results 241 to 250 of about 3,352,860 (301)

Ionomycin suppresses cancer cell growth by disrupting mitochondrial transcription

FEBS Open Bio, EarlyView.
In this study, we identify a new function for the selective Ca2+ ionophore, ionomycin, as an inhibitor of mitochondrial transcription. Both total and nascent RNA analyses revealed that ionomycin treatment reduces the transcription of mitochondrial genes.
Lishen Wang, Mingqiang Deng, Dongmei He, Diqin Lai, Dongjun Liu, Dengyong Zhu, Zhenhua Zhang, Peng Tang, Chuanman Zhou, Menghui Yin, Xichen Bao   +10 more
wiley   +1 more source

An empirical dataset combining repository metrics and pipeline workflows for predictive software analytics. [PDF]

Data Brief
Sanusi FA, Faruna JO.
europepmc   +1 more source

Exploring the influence of lactoferrin on wound healing and related signaling pathways: a systematic review

FEBS Open Bio, EarlyView.
Lactoferrin promotes wound healing by activating MAPK, PI3K/Akt, and extracellular matrix pathways, enhancing fibroblast remodeling, proliferation, and re‐epithelialization. These mechanisms highlight its therapeutic potential in inflammation control, tissue repair, and remodeling.
Morgana Lüdtke Azevedo, Kátia Cristiane Hall, Matheus dos Santos Fernandez, Geovanna Peter Corrêa, Rafael Guerra Lund   +4 more
wiley   +1 more source

Slide-free FIBI histology for improved quantitative vascular network analysis in breast cancer: Integrating vessel geometry and topology metrics. [PDF]

J Pathol Inform
Brown S, Anderson N, Orozco J, Levenson R.   +3 more
europepmc   +1 more source

Dose‐dependent hepatotoxicity of hydrogen peroxide in HepG2 cells and its modulation by CYP450 induction

FEBS Open Bio, EarlyView.
NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks, Garth L. Maker, Emily C. Davies, Berin A. Boughton, Samantha Lodge   +4 more
wiley   +1 more source

Perivascular diffusion and white matter free water improve identification of cognitive impairment in cerebral small vessel disease. [PDF]

Front Neurol
Yang C, Cai S, Wang B, Zhou J, Wu D, Li M, Geng W, Wu L, Peng K, Yang Y, Gu W.   +10 more
europepmc   +1 more source

Augmenting patient safety surveillance in radiation oncology with large language model-based root cause analysis: A proof-of-concept study. [PDF]

PLOS Digit Health
Wang Y, De Ornelas M, Studenski MT, Bossart E, Nejad-Davarani SP, Yang Y.   +5 more
europepmc   +1 more source

Purkinje Cell Loss and Changes in Basket Cell Morphology in Essential Tremor and Other Cerebellar Degenerative Diseases: A Postmortem Study of 332 Brains. [PDF]

Cerebellum
Wainman E, Guy TO, Hernandez N, Faust PL, Louis ED.   +4 more
europepmc   +1 more source

Intermethod Association in Orthodontic White Spot Lesion Assessment: A Multimodal-Assessment. [PDF]

Int Dent J
Firinciogullari EC, Agani Sabah G, Erdinc AM, Uner B.   +3 more
europepmc   +1 more source

Impact of Recording Conditions and Feature Fusion on Dementia Classification Using Spectral, Entropy, and Complexity EEG Features. [PDF]

Entropy (Basel)
Sari K, Kouchaki S, Abasolo D.
europepmc   +1 more source