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Recent advances in combined modality therapy. [PDF]
Abstract Combined modality therapy emerged from preclinical data showing that carefully chosen drugs could enhance the sensitivity of tumor cells to radiation while having nonoverlapping toxicities. Recent advances in molecular biology involving the identification of cellular receptors, enzymes, and pathways involved in tumor growth and ...
Mierzwa ML+3 more
europepmc +9 more sources
Targeted radionuclide therapy in combined-modality regimens [PDF]
Targeted radionuclide therapy (TRT) is a branch of cancer medicine concerned with the use of radioisotopes, radiolabelled molecules, nanoparticles, or microparticles that either naturally accumulate in or are designed to target tumours. TRT combines the specificity of molecular and sometimes physical targeting with the potent cytotoxicity of ionising ...
Gill, MR, Falzone, N, Du, Y, Vallis, KA
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Prostatic Leiomyosarcoma: The Case for Combined Modality Therapy [PDF]
Patient. A 65‐year old man who had previously undergone surgery for benign prostatic hyperplasia presented with symptoms of recurrent bladder outflow obstruction. Cystoscopy revealed the presence of recurrent tissue.Results. Histology identified a leiomyosarcoma.
Keith Vaughton, Salah El-Sharkawi
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Combined Modality Therapy of Gemcitabine and Radiation [PDF]
Abstract Learning Objectives After completing this course, the reader will be able to: List the advantages of combination chemotherapy and radiotherapy. Explain the rationale for doing in vitro research in the radiochemotherapy field.
Pauwels, Bea+3 more
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Combined modality therapy of Ewing's sarcoma [PDF]
Since 1964, 66 consecutive patients with Ewing's sarcoma have been treated at the National Cancer Institute with local irradiation of the primary site combined with adjuvant regimens of progressively more intensive systemic chemotherapy. Actuarial survival rates for the total series show a 56% 2-year and 35% 5-year survival.
Thomas C. Pomeroy, Ralph E. Johnson
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Neutron Therapy for Salivary and Thyroid Gland Cancer [PDF]
The purpose of this study was to analyze the results of the combined modality treatment and radiation therapy using 6.3 MeV fast neutrons for salivary gland cancer and prognostically unfavorable thyroid gland cancer.
Choynzonov, Evgeny Lkhamatsyrenovich+4 more
core +1 more source
External radiotherapy of thyroid cancer [PDF]
Differentiated thyroid cancer comprises papillary, mixed papillary-follicular and follicular adenocarcinomas. They are mostly hormone-sensitive and respond to thyroid-stimulating hormone (TSH) suppression. The standard treatment is total thyroidectomy. I-
Dühmke, Eckhart, Pollinger, B.
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Successful Treatment of Stereotactic Body Radiation Therapy Combined with Transarterial Chemolipiodolization for Hepatocellular Carcinoma with Biliary Obstruction [PDF]
Conventional radiation therapy (RT) is a widely recognized treatment for hepatocellular carcinoma (HCC). However, conventional RT plays only a limited role in HCC treatment because of its low efficacy and the low tolerance of the liver for this modality.
Blomgren+20 more
core +2 more sources
Combined modality therapy of rectal cancers
Rectal cancer accounts for about 10% of new cancer cases each year. It strikes men and women at nearly the same rate, generally in the range of 50-80 years of age, with rising incidence with age. Despite simple screening procedures rectal cancer is often advanced when discovered.
Hrvoje Šobat+2 more
openaire +4 more sources
A perspective on the impact of radiation therapy on the immune rheostat. [PDF]
The advent and success of immune checkpoint inhibitors (ICIs) in cancer treatment has broadened the spectrum of tumours that might be considered "immunogenic" and susceptible to immunotherapeutic (IT) intervention. Not all cancer types are sensitive, and
Ganapathy, Ekambaram+5 more
core +1 more source