Results 41 to 50 of about 5,027,784 (302)
Pulmonary toxicity with combined modality therapy for limited stage small-cell lung cancer.
, 1986 To assess the pulmonary toxicity of radiation therapy combined with chemotherapy v chemotherapy alone, we reviewed the clinical course of 80 patients with limited stage small-cell lung cancer treated in a randomized prospective trial.
M H Cohen +9 more
core +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Conceivability, Apriority and Modality [PDF]
, 2011 I aim to understand whether apriority entails necessity, aposteriority entails contingency and conceivability entails possibility; that is, the relationship between, and the nature of, rationality and modality.
WINSTANLEY, PAUL
core
Exploratory RCT of art therapy as an adjunctive treatment in schizophrenia [PDF]
, 2007 Background There is no high quality controlled trial evidence for the effectiveness of art therapy in the adjunctive treatment of schizophrenia. Aims To conduct the first exploratory RCT of group interactive art therapy (AT) as an adjunctive ...
Richardson, Phil +5 more
core +1 more source
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
Combination Therapies in Ophthalmology: Implications for Intravitreal Delivery
Journal of Ophthalmic & Vision Research, 2011 Most pathological processes involve complex molecular pathways that can only be modified or blocked by a combination of medications. Combination therapy has become a common practice in medicine.
Gholam A Peyman, Kamran Hosseini
doaj
Intestinal-type adenocarcinoma of nasal cavity: A case series
Asian Journal of Medical SciencesSinonasal intestinal-type adenocarcinomas (ITACs) are uncommon, high-grade epithelial tumors of the nasal cavity and paranasal sinuses with an annual incidence of
Moanaro Longchar +3 more
doaj +1 more source
Chinese Journal of Lung Cancer, 2022 Cachexia is a common complication in patients with lung cancer. It aggravates the toxic and side effects of chemotherapy, hinders the treatment plan, weakens the responsiveness of chemotherapy, reduces the quality of life, increases complications and ...
Jiemin WANG +7 more
doaj +1 more source