Results 51 to 60 of about 289,359 (304)

Primary endocrine therapy of locally advanced breast cancer patients [PDF]

Archive of Oncology, 2003
Primary endocrine therapy has been traditionally reserved for elderly and unfit locally advanced breast cancer patients (LABC patients). In this group, the primary endocrine therapy could not be adequately compared to primary chemotherapy.
Nešković-Konstantinović Zora B.
doaj   +1 more source

Targeted radionuclide therapy in combined-modality regimens [PDF]

The Lancet Oncology, 2017
Targeted radionuclide therapy (TRT) is a branch of cancer medicine concerned with the use of radioisotopes, radiolabelled molecules, nanoparticles, or microparticles that either naturally accumulate in or are designed to target tumours. TRT combines the specificity of molecular and sometimes physical targeting with the potent cytotoxicity of ionising ...
Gill, MR, Falzone, N, Du, Y, Vallis, KA
openaire   +4 more sources

Evaluation of Xpert® MTB/RIF and ustar easyNAT™ TB IAD for diagnosis of tuberculous lymphadenitis of children in Tanzania : a prospective descriptive study [PDF]

, 2016
Fine needle aspiration biopsy has become a standard approach for diagnosis of peripheral tuberculous lymphadenitis. The aim of this study was to compare the performance of Xpert MTB/RIF and Ustar EasyNAT TB IAD nucleic acid amplification assays, against ...
AT Cruz, CA Wright, CA Wright, CA Wright, CC Anunobi, CC Boehme, CJL Murray, CM Denkinger, CM Denkinger, CM Perez-Velez, D Hillemann, E Penz, Edward Masika, ES Cibas, F Ardito, FA Mhimbira, Hans-Peter Beck, Hassan Chande, J Ayugi, J Cohen, JA Seddon, JB Reitsma, Klaus Reither, L Coetzee, Levan Jugheli, M Pai, Maira Bholla, Mohamed Sasamalo, Neema Kapalata, PJ Dodd, R Fang, RR Kazwala, S Chakravorty, SGM Mfinanga, SH Siddiqi, SM Newton, Tracy R. Glass, Ustar Biotechnologies, World Health Organization, X Ou   +39 more
core   +3 more sources

Prognosis of Long‐Term Continuous Renal Replacement Therapy and the Impact of Combined Continuous Intravenous Sodium Infusion Therapy

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Patients requiring long‐term continuous renal replacement therapy (CRRT) generally have poor prognoses. This study evaluated whether adding continuous intravenous sodium infusion (cIVNa) is associated with improved hemodynamics and outcomes in patients undergoing long‐term CRRT for ≥ 7 days.
Akinori Yamaguchi, Atsuyoshi Mita, Kosuke Sonoda, Makoto Harada, Koji Hashimoto, Hiroshi Imamura, Yuji Kamijo   +6 more
wiley   +1 more source

Combined Modality Therapies for High-Risk Prostate Cancer: Narrative Review of Current Understanding and New Directions. [PDF]

, 2019
Despite the many prospective randomized trials that have been available in the past decade regarding the optimization of radiation, hormonal, and surgical therapies for high-risk prostate cancer (PCa), many questions remain.
Chen, Victor E., Den, Robert B., Greenberger, Benjamin A.   +2 more
core   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, Volume 20, Issue 6, Page 1398-1419, June 2026.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

Research Progress of Pharmacological Therapy and Nutritional Support for Cachexia 
in Lung Cancer Patients

Chinese Journal of Lung Cancer, 2022
Cachexia is a common complication in patients with lung cancer. It aggravates the toxic and side effects of chemotherapy, hinders the treatment plan, weakens the responsiveness of chemotherapy, reduces the quality of life, increases complications and ...
Jiemin WANG, Weihui JIA, Danyang LI, Yanmei SONG, Ningxin SUN, Ke YANG, Hongli LI, Chonggao YIN   +7 more
doaj   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

Molecular Oncology, Volume 20, Issue 6, Page 1626-1642, June 2026.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon, Peter T. Gallagher, Orly I. Richter, Neermala Poudel Neupane, Amy C. Mandigo, Jennifer J. McCann, Emanuela Dylgjeri, Irina Vasilevskaya, Christopher McNair, Channing J. Paller, Wm. Kevin Kelly, Karen E. Knudsen, Matthew J. Schiewer, Ayesha A. Shafi   +13 more
wiley   +1 more source

Combination Therapies in Ophthalmology: Implications for Intravitreal Delivery

Journal of Ophthalmic & Vision Research, 2011
Most pathological processes involve complex molecular pathways that can only be modified or blocked by a combination of medications. Combination therapy has become a common practice in medicine.
Gholam A Peyman, Kamran Hosseini
doaj  

Neoadjuvant Concurrent Chemoradiation in Locally Advanced Adenocarcinoma of Gastroesophageal Junction & Proximal Stomach (A Single Arm Study): Our Experience From Single Institute From Kashmir Valley

JK Science, 2023
Introduction: The aim of this study was to investigate the efficacy and safety of using a neo-adjuvant concomitant chemoradiation therapy to treat potentially resectable adenocarcinoma of the gastroesophageal junction & proximal stomach.
Murtaza Shafi, Mohammad Maqbool Lone, Mushtaq Ahmad Sofi, Khursheed Alam Wani, Gul Mohammad Bhat, Tavseef Ahmad Tali, Mansoora Akhter   +6 more
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