Results 61 to 70 of about 5,395,673 (305)

Escape Rooms as an Effective Teaching Modality for Occupational Therapy Students

, 2022
This project aims to determine if using escape rooms as a form of gamification might benefit occupational therapy students. Occupational Therapy and Occupational Therapy Assistant students were randomly paired and assigned to an online or in-person ...
Fan, Chia-Wei
core  

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

Molecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq, Marc Terrones, Felicia Rodrigues Fortes, Anne Schepers, Alessia Denis, Christophe Deben, Ken Op de Beeck, Guy Van Camp, Geert Vandeweyer   +8 more
wiley   +1 more source

Multimodal analgesia versus patient-controlled analgesia in the management of acute postoperative spinal pain: systematic review and meta-analysis

BrJP
BACKGROUND AND OBJECTIVES: Spine diseases have a high annual prevalence and are the main causes of years lived with disability and chronic pain. Among the postoperative analgesic control options, patient-controlled analgesia (PCA) and multimodal ...
Lucas de Melo Castro Deligne, Guilherme Baldez Pinheiro, Marcelo de Oliveira Peres, André Moreira Castilho   +3 more
doaj   +1 more source

Dual-modality PET/CT instrumentation-today and tomorrow

, 2010
Positron emission tomography (PET) has proven to be a clinically valuable imaging modality, particularly for oncology staging and therapy follow-up.
Beyer, Thomas, Lonsdale, Markus Nowak, Markus Nowak Lonsdale, Thomas Beyer   +3 more
core   +1 more source

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

Molecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach, Gizem Abaci, Tom Huberty, Axel Lechner, Lukas Käsmann, Jens Ricke, Sophia Stöcklein, Martin Canis, Philipp Baumeister, Marianna Alunni‐Fabbroni   +9 more
wiley   +1 more source

Clinical Application of Adjuvant Treatment after Operation in Patients with Stage IIIa Non-small Cell Lung Cancer

Chinese Journal of Lung Cancer, 2010
Background and objective The efficacy of complete resection of the cancer for patients with stage IIIa non-small cell lung cancer (NSCLC) is limited. Synthetic therapy is taken the lead in advocating at present.
Yajie GAO, Bin ZHANG, Xia ZHANG
doaj  

Neoadjuvant Concurrent Chemoradiation in Locally Advanced Adenocarcinoma of Gastroesophageal Junction & Proximal Stomach (A Single Arm Study): Our Experience From Single Institute From Kashmir Valley

JK Science, 2023
Introduction: The aim of this study was to investigate the efficacy and safety of using a neo-adjuvant concomitant chemoradiation therapy to treat potentially resectable adenocarcinoma of the gastroesophageal junction & proximal stomach.
Murtaza Shafi, Mohammad Maqbool Lone, Mushtaq Ahmad Sofi, Khursheed Alam Wani, Gul Mohammad Bhat, Tavseef Ahmad Tali, Mansoora Akhter   +6 more
doaj  

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

Molecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche, Niels J. van Ruitenbeek, Charlotte Adang, Luke O'Gorman, Pui Yuen Lee, Willemijn M. Klein, Adriana C. H. van Engen‐van Grunsven, Jack A. Schalken, Sander Bervoets, Gerald W. Verhaegh, Carla M. L. van Herpen   +10 more
wiley   +1 more source

Local control and toxicity outcomes following consolidative radiation therapy in patients with high-risk neuroblastoma: a 20-year experience at a single center

The Turkish Journal of Pediatrics
Background. Intensive multimodal treatment can improve survival in patients with high-risk neuroblastoma, and consolidative radiation therapy has contributed to local control.
Jeong Yun Jang, Jin-Hong Park, Yeon Joo Kim, Ho Joon Im, Kyung-Nam Koh, Hyery Kim, Sung Han Kang, Ha Un Kim, Seung Do Ahn   +8 more
doaj   +1 more source

Prostatic Leiomyosarcoma: The Case for Combined Modality Therapy [PDF]

Sarcoma, 1997
Patient. A 65‐year old man who had previously undergone surgery for benign prostatic hyperplasia presented with symptoms of recurrent bladder outflow obstruction. Cystoscopy revealed the presence of recurrent tissue.Results. Histology identified a leiomyosarcoma.
El-Sharkawi, Salah, Vaughton, Keith
openaire   +2 more sources