Results 71 to 80 of about 289,359 (304)

Prostatic Leiomyosarcoma: The Case for Combined Modality Therapy [PDF]

open access: yesSarcoma, 1997
Patient. A 65‐year old man who had previously undergone surgery for benign prostatic hyperplasia presented with symptoms of recurrent bladder outflow obstruction. Cystoscopy revealed the presence of recurrent tissue.Results. Histology identified a leiomyosarcoma.
El-Sharkawi, Salah, Vaughton, Keith
openaire   +2 more sources

Monitoring Breast Cancer Response to Neoadjuvant Chemotherapy Using Ultrasound Strain Elastography [PDF]

open access: yes, 2019
© 2019 The Authors Strain elastography was used to monitor response to neoadjuvant chemotherapy (NAC) in 92 patients with biopsy-proven, locally advanced breast cancer. Strain elastography data were collected before, during, and after NAC.
Curpen, B.   +12 more
core   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

EWING TUMOR: DIFFERENTIAL DIAGNOSIS AND BASIS FOR ONCOLOGICAL AND SURGICAL TREATMENT [PDF]

open access: yesColuna/Columna
Ewing sarcoma (ES) is a highly aggressive primary bone tumor that poses significant diagnostic and therapeutic challenges when affecting the spinal column.
Debora Yumi Yoshimura Orlandin Alves   +3 more
doaj   +1 more source

Joint versus separate inpatient rehabilitation treatment for patients with alcohol use disorder or drug use disorder : an observational study [PDF]

open access: yes, 2018
Background: In many national treatment systems, patients with alcohol use disorders (AUD) and those with drug use disorders (DUD) are treated separately, while other systems provide joint treatment for both kinds of substance use disorders (SUDs ...
Bender, Stefan   +7 more
core   +2 more sources

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

Best evidence rehabilitation for chronic pain, part 3 : low back pain [PDF]

open access: yes, 2019
Chronic Low Back Pain (CLBP) is a major and highly prevalent health problem. Given the high number of papers available, clinicians might be overwhelmed by the evidence on CLBP management.
Bilterys, Thomas   +9 more
core   +2 more sources

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Psychosocial treatments for negative symptoms in schizophrenia: current practices and future directions. [PDF]

open access: yes, 2013
Schizophrenia can be a chronic and debilitating psychiatric disorder. Though advancements have been made in the psychosocial treatment of some symptoms of schizophrenia, people with schizophrenia often continue to experience some level of symptoms ...
Caponigro, Janelle M   +2 more
core  

Primary CNS Lymphoma [PDF]

open access: yes, 2014
Primary diffuse large B-cell lymphoma (DLBCL) of the central nervous system is an aggressive malignancy that exhibits unique biological features and characteristic clinical behaviour, with overall long-term survival rates of around 20–40 %.
Cwynarski, K, Fox, CP, Phillips, EH
core   +1 more source

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