Results 131 to 140 of about 746,495 (300)

The business aspects of combined transport

open access: yes, 2017
Diplomová práce je zaměřena na problematiku kombinované přepravy silnice-železnice. Práce se zabývá významem kombinované přepravy, analýzou jejího současného stavu, právní úpravou a podmínkami podnikání včetně smluvního zabezpečení a odpovídajícího ...
Holický, Ondřej
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Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

open access: yesMolecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen   +9 more
wiley   +1 more source

DEVELOPMENT OF CONTINENTAL COMBINED TRANSPORT IN THE CZECH REPUBLIC

open access: yes, 2016
V příspěvku byly popsány jak současná situace kombinované dopravy a zejména dopravy kontinentální v ČR a aspekty jejího dalšího možného rozvoje. Velmi významné je využití kontinentální KD v logistických řetězcích a to zejména při přepravě paletovaného ...
Cempírek, Václav   +3 more
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ESR1 methylation and ESR1 mutations in circulating tumor cells (CTCs) and paired plasma‐cfDNA of advanced breast cancer patients: A feasibility proof‐of‐concept study

open access: yesMolecular Oncology, EarlyView.
Circulating tumor cells (CTCs) and plasma cell‐free DNA (cfDNA) were analyzed to detect ESR1 mutations and methylation in patients with advanced breast cancer. CTC‐derived DNA showed higher sensitivity for mutation detection and revealed complementary genetic and epigenetic alterations, highlighting the added value of CTC analysis for understanding ...
Dimitra Stergiopoulou   +12 more
wiley   +1 more source

Accompanied combined transport

open access: yes, 2012
Práce je věnována problematice doprovázené kombinované přepravy. Její podstatu tvoří analýza systémů Ro-La a Modalohr a srovnání nákladů a času potřebného pro přímou silniční nákladní přepravu a kombinovanou přepravu.The bachelor thesis is focused on ...
Borovičková, Lina
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Motor Transport Service parking area for Stilwell Road convoys.

open access: yes, 2020
Caption: Motor Transport Service parking area for Stilwell Road convoys. This area, in China, was without tents for drivers when photo was made 12 May 1945.

core  

Interpreting the effects of DNA polymerase variants at the structural level

open access: yesMolecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi   +7 more
wiley   +1 more source

Transporter Scheduling with Transporter Combination in Shipbuilding

open access: yesJournal of Navigation and Port Research, 2014
Jae-Young Shin, Na-Hyun Bak
openaire   +2 more sources

Relationship between civil and military air transport agencies.

open access: yes, 2008
This student paper studies the relationship between civil and military air transport agencies, past and present, and analyzes the future relationship that should obtain to effect maximum efficient utilization of all air transportation in event of a ...
Singer, David M.
core  

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata   +10 more
wiley   +1 more source

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