Results 251 to 260 of about 2,423,331 (345)

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Heterotic grouping of wheat hybrids based on general and specific combining ability from line × tester analysis. [PDF]

PeerJ
Deviren B, Bilgin O, Kutlu I.
europepmc   +1 more source

Diallel analysis for combining ability in Brinjal [PDF]

, 1990
S. N. Mishra, R. S. Mishra
openalex  

Targeting p38α in cancer: challenges, opportunities, and emerging strategies

Molecular Oncology, EarlyView.
p38α normally regulates cellular stress responses and homeostasis and suppresses malignant transformation. In cancer, however, p38α is co‐opted to drive context‐dependent proliferation and dissemination. p38α also supports key functions in cells of the tumor microenvironment, including fibroblasts, myeloid cells, and T lymphocytes.
Angel R. Nebreda
wiley   +1 more source

Combining Ability of Capsicum annuum Hybrid for Antioxidant Activities, Polyphenol Content, α-Glucosidase Inhibitory, Yield, and Yield Components. [PDF]

Curr Issues Mol Biol
Syukur M, Maharijaya A, Nurcholis W, Ritonga AW, Pangestu AY, Hatta ANNL, Istiqlal MRA, Hakim A, Sahid ZD.   +8 more
europepmc   +1 more source

Combining ability analysis in lathyrus

International Journal of Advanced Biochemistry Research
Dr. Vandana S. Madke, Dr. S. A. Patil, Dr. Ashwini A. Mankar, KC Pardhi   +3 more
openaire   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Combining ability for agronomic traits among commercial maize hybrids under low and high nitrogen inputs targeting the development of breeding populations. [PDF]

PLoS One
Luz LS, Reis HMD, de Leon da Costa NMEP, Carvalho FR, Caixeta DG, DeLima RO.   +5 more
europepmc   +1 more source

COMBINING ABILITY AND GENE ACTION ANALYSIS USING LINE × TESTER IN GREEN GRAM (VIGNA RADIATA L.)

Murakonda Sai Dinesh, Rajneesh Kumar, I.R. Delvadiya, Manisha Satyawan Mote, Kamilla Priyatham, Iram Bashir, Suman Paree, Mouli Paul, Mukesh Vishnoi, Dhamni Patyal, Ajaz A. Lone   +10 more
openalex   +1 more source

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

Molecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon, Dong Young Kim, Yuna Kim, Uk‐Il Kim, Jae‐Sung Kim   +4 more
wiley   +1 more source