Results 251 to 260 of about 2,304,826 (345)

COMBINING ABILITY STUDIES FOR FODDER ATTRIBUTES IN SWEET PEARL MILLET [PDF]

, 1996
A LOGASUNDARI, FAZLULLAH KHAN A.K
openalex   +1 more source

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

Molecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié, Davod R. Shah, Eliane E. S. Brechbühl, Michael McNicholas, Zhaoyang Xu, John H. Stockley, Laura Morcom, Diana Gold Diaz, Gemma C. Girdler, Rachel V. Seear, Gabriel Balmus, Rajiv R. Ratan, Harry Bulstrode, James A. Nathan, Manav Pathania, Kevin M. Brindle, David H. Rowitch   +16 more
wiley   +1 more source

Combining ability analysis of Cucurbita moschata D. in Côte d'Ivoire and classification of promising lines based on their gca effects. [PDF]

PLoS One
Kouago BA, Seka D, Brou KF, Bonny BS, Koffi KHJ, Adjoumani K, Sie RS.   +6 more
europepmc   +1 more source

Combining Ability and Performance of Extra-Early Maturing Provitamin A Maize Inbreds and Derived Hybrids in Multiple Environments. [PDF]

Plants (Basel), 2022
Oluwaseun O, Badu-Apraku B, Adebayo M, Abubakar AM.   +3 more
europepmc   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

Testcross performance and combining ability of intermediate maturing drought tolerant maize inbred lines in Sub-Saharan Africa. [PDF]

Front Plant Sci
Manigben KA, Beyene Y, Chaikam V, Tongoona PB, Danquah EY, Ifie BE, Aleri I, Chavangi A, Prasanna BM, Gowda M.   +9 more
europepmc   +1 more source

Diallel analysis of the combining ability of common bean (Phaseolus vulgaris L.) cultivars [PDF]

, 2000
Marco Antônio Aparecido Barelli, Maria Celeste Gonçalves‐Vidigal, Antônio Teixeira do Amaral Júnior, Pedro Soares Vidigal Filho, Carlos Alberto Scapim   +4 more
openalex   +1 more source

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

Molecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad, Rhiannon Newman, Elmira Khabusheva, Sofia Aakko, Eric Durand, Mahesh Tambe, Heikki Kuusanmäki, Alun Parsons, Juho J. Miettinen, Komal Kumar Javarappa, Ezgi June Olgac, Nemo Ikonen, Mika Kontro, Kimmo Porkka, Heiko Maacke, Janghee Woo, Ensar Halilovic, Caroline A. Heckman   +17 more
wiley   +1 more source

Heterotic grouping of wheat hybrids based on general and specific combining ability from line × tester analysis. [PDF]

PeerJ
Deviren B, Bilgin O, Kutlu I.
europepmc   +1 more source

Screening the Cucumber Germplasm Collection for Combining Ability for Yield [PDF]

, 2000
Todd C. Wehner, Nischit V. Shetty, Raymond L. Clark   +2 more
openalex   +1 more source