Results 81 to 90 of about 2,304,826 (345)

Goodbye flat lymphoma biology

FEBS Letters, EarlyView.
Three‐dimensional (3D) biological systems have become key tools in lymphoma research, offering reliable in vitro and ex vivo platforms to explore pathogenesis and support precision medicine. This review highlights current 3D non‐Hodgkin lymphoma models, detailing their features, advantages, and limitations, and provides a broad perspective on future ...
Carla Faria, Cèlia Dobaño‐López, Patricia Pérez‐Galán, Christine Bezombes   +3 more
wiley   +1 more source

From omics to AI—mapping the pathogenic pathways in type 2 diabetes

FEBS Letters, EarlyView.
Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan, Lu Qi, Pierre Zalloua   +2 more
wiley   +1 more source

Estimating Combining Ability Effect of the Indian and Exotic Lines of Tomatoes by Partial Diallel Analysis

Turkish Journal of Agriculture: Food Science and Technology, 2015
Eight nearly homozygous, horticulturally superior and optimally divergent lines of tomato having Indian and exotic adaptability were used for carrying out half diallel design to study General Combining Ability (GCA) and Specific Combining Ability (SCA ...
Suresh Baban Dagade, Nanadasana Jagdish Nasibhai, Hariprasanna Krishna, Bhatt Virendra Mulshankar, Dhaduk Lallubhai Keshavbhai, Barad Agarsang Virsanbhai   +5 more
doaj   +1 more source

Exploring lipid diversity and minimalism to define membrane requirements for synthetic cells

FEBS Letters, EarlyView.
Designing the lipid membrane of synthetic cells is a complex task, in which its various roles (among them solute transport, membrane protein support, and self‐replication) should all be integrated. In this review, we report the latest top‐down and bottom‐up advances and discuss compatibility and complexity issues of current engineering approaches ...
Sergiy Gan, Victoria Scarpelli, Marten Exterkate   +2 more
wiley   +1 more source

General and specific combining ability in sweet sorghum [PDF]

Crop Breeding and Applied Biotechnology, 2018
In breeding of sweet sorghum hybrids, non-additive genetic effects are important in phenotypic expression of the traits of interest. The aim of this study was to evaluate the general combining ability (GCA) of sweet sorghum lines and the specific combining ability (SCA) of the hybrids for agronomic and technological traits.
Rocha, Mara Jane da, Nunes, José Airton Rodrigues, Parrella, Rafael Augusto da Costa, Leite, Pakizza Sherma da Silva, Lombardi, Gabrielle Maria Romeiro, Moura, Mayra Luiza Costa, Schaffert, Robert Eugene, Bruzi, Adriano Teodoro   +7 more
openaire   +4 more sources

Ergothioneine supplementation improves pup phenotype and survival in a murine model of spinal muscular atrophy

FEBS Letters, EarlyView.
Spinal muscular atrophy (SMA) is a genetic disease affecting motor neurons. Individuals with SMA experience mitochondrial dysfunction and oxidative stress. The aim of the study was to investigate the effect of an antioxidant and neuroprotective substance, ergothioneine (ERGO), on an SMNΔ7 mouse model of SMA.
Francesca Cadile, Daniela Ratto, Giorgia Rastelli, Ottavia Eleonora Ferraro, Caterina Temporini, Sunil Kumar, Simona Boncompagni, Paola Rossi, Monica Canepari   +8 more
wiley   +1 more source

Studies on Combining Ability for Yield and Quality Traits in Brinjal (Solanum melongena L.)

Journal of Horticultural Sciences, 2012
The experimental material in brinjal (eggplant) comprised 19 parents (15 lines + 4 testers), 60 F1 crosses and two standard checks (BH-1 and BH-2). This was grown in Randomized Block Design, with three replications. Lines vs.
Bharat Bhushan, A S Sidhu, A S Dhatt, Ajay Kumar   +3 more
doaj   +1 more source

Microbial exopolysaccharide production by polyextremophiles in the adaptation to multiple extremes

FEBS Letters, EarlyView.
Polyextremophiles are microorganisms that endure multiple extreme conditions by various adaptation strategies that also include the production of exopolysaccharides (EPSs). This review provides an integrated perspective on EPS biosynthesis, function, and regulation in these organisms, emphasizing their critical role in survival and highlighting their ...
Tracey M Gloster, Ebru Toksoy Öner
wiley   +1 more source

Particle Swarm Optimization: An efficient method for tracing periodic orbits in 3D galactic potentials

, 2005
We propose the Particle Swarm Optimization (PSO) as an alternative method for locating periodic orbits in a three--dimensional (3D) model of barred galaxies. We develop an appropriate scheme that transforms the problem of finding periodic orbits into the
Parsopoulos, K. E., Patsis, P. A., Skokos, Ch., Vrahatis, M. N.   +3 more
core   +1 more source

Structural dynamics of the plant hormone receptor ETR1 in a native‐like membrane environment

FEBS Letters, EarlyView.
The present study unveils the structural and signaling dynamics of ETR1, a key plant ethylene receptor. Using an optimized nanodisc system and solution NMR, we captured full‐length ETR1 in a native‐like membrane environment. Our findings reveal dynamic domain uncoupling and Cu(I)‐induced rigidification, providing the first evidence of metal‐triggered ...
Moritz Lemke, Nils Alexander Lakomek, Georg Groth   +2 more
wiley   +1 more source