Results 91 to 100 of about 6,242 (256)

A minimal physiologically‐based pharmacokinetic modeling platform to predict intratumor exposure and receptor occupancy of an anti‐LAG‐3 monoclonal antibody

open access: yesCPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 460-473, March 2025.
Abstract In oncology drug development, measuring drug concentrations at the tumor site and at the targeted receptor remains an ongoing challenge. Positron emission tomography (PET)‐imaging is a promising noninvasive method to quantify intratumor exposure of a radiolabeled drug (biodistribution data) and target saturation by treatment doses in vivo ...
Robin Michelet   +8 more
wiley   +1 more source

Reasoning Together or Clicking Through? Analyzing Patterns of Group Science Talk On and Off Individualized Computers

open access: yesScience Education, EarlyView.
ABSTRACT In this article, I examine group science talk within the classrooms of three urban secondary science teachers who regularly use one‐to‐one computers to mediate their NGSS‐aligned science instruction. I combine methods of framing analysis (Goffman 1974; Tannen 1993) and interaction analysis (Jordan and Henderson 1995) to illustrate differences ...
Tess Bernhard
wiley   +1 more source

Micro‐transitions and work identity: The case of academic entrepreneurs

open access: yesStrategic Entrepreneurship Journal, EarlyView.
Abstract Research Summary This paper examines how academic entrepreneurs—scientists who found research‐based startups while remaining in academia—construct and sustain their professional identities amid frequent transitions between academic and entrepreneurial roles.
Marouane Bousfiha, Henrik Berglund
wiley   +1 more source

Framing novelty in crowdfunding: Which words win support, where, and at what stakes

open access: yesStrategic Entrepreneurship Journal, EarlyView.
Abstract Research Summary We examine how promotional language (“hype”) in reward‐based crowdfunding is associated with campaign success, and whether those associations vary across sector contexts and with campaign execution burden. Using dictionary‐based text measures from 635 U.S. Kickstarter campaigns across five sectors, we distinguish three novelty‐
Agnieszka Kwapisz
wiley   +1 more source

Mixed feelings, mixed outcomes? When emotionally ambivalent framing enhances idea appreciation

open access: yesStrategic Entrepreneurship Journal, EarlyView.
Abstract Research Summary Despite growing interest in how linguistic strategies shape audience responses to innovative ideas, prior evidence on the benefits of using emotional language remains mixed. Building on research on emotional ambivalence and social evaluation, we introduce the concept of emotionally ambivalent framing (i.e., the combination of ...
Donato Cutolo   +2 more
wiley   +1 more source

Semester in Dialogue: A Systems Thinking Approach to Dialogue‐Based Higher Education at Simon Fraser University

open access: yesSystems Research and Behavioral Science, EarlyView.
ABSTRACT This paper addresses a gap in the application of systems thinking to higher education programme design. We use the Complexity Theory of Outcome Creation (CTOC), a structured model for working in complexity, to analyse Simon Fraser University's Semester in Dialogue (SiD)—an innovative undergraduate programme applying the ideas of dialogic ...
Diane T. Finegood   +2 more
wiley   +1 more source

Embedded Interactions and Selective Disclosure: Network Effects on Conversations aboard Skylab

open access: yesSymbolic Interaction, EarlyView.
How do absent others influence our interactions? We argue in this paper that interactions are embedded within networks formed by chains of specific relationships between known third parties. The anticipation of future interactions with external others conditions our interpretation of the current situation and affects our behavior in the interaction. We
Michael Schultz   +2 more
wiley   +1 more source

An Outline of a Theory of Play

open access: yesSymbolic Interaction, EarlyView.
Play is often dismissed as trivial, yet it is a fundamental and adaptive aspect of human and mammalian life. This paper develops a sociological theory of play, treating it as a total social fact that spans biological, psychological, and social dimensions.
Seth Abrutyn
wiley   +1 more source

Identity Entanglement: Rethinking Marginality through the Intersectional, Liminal, and Antithetical

open access: yesSymbolic Interaction, EarlyView.
While identity research has given sustained attention to marginality, intersectionality, and the effects of power on identity, the formal interactional dynamics through which identities are constituted remain limited. I present identity entanglement as a useful framework for better understanding and articulating the relational complexities of identity.
Jules Vivid
wiley   +1 more source

Incidental Acquisition of Multiword Expressions Through Repeated Viewing: Sequential Use of L1 and L2 Captions

open access: yesTESOL Quarterly, EarlyView.
Abstract Repeated viewing is reportedly a common learning and pedagogical strategy among autonomous second language (L2) learners and language teachers. This experimental study examined the extent to which sequential captioning use facilitates the acquisition of multiword expressions (MWEs) through repeated viewing under incidental learning conditions.
Kenneth W. Y. Li, Yaxin Ni
wiley   +1 more source

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