Results 161 to 170 of about 291,896 (358)
Environmental and Molecular Mutagenesis, EarlyView.Abstract Exposure levels without appreciable human health risk may be determined by dividing a point of departure on a dose–response curve (e.g., benchmark dose) by a composite adjustment factor (AF). An “effect severity” AF (ESAF) is employed in some regulatory contexts.
Barbara L. Parsons +17 more
wiley +1 more source
Environmental and Molecular Mutagenesis, EarlyView.Abstract In human health risk assessment of chemicals and pharmaceuticals, identification of genotoxicity hazard usually starts with a standard battery of in vitro genotoxicity tests, which is needed to cover all genotoxicity endpoints. The individual tests included in the battery are not designed to pick up all endpoints.
Mirjam Luijten +15 more
wiley +1 more source
The Comparison Of New Web Communication Method WebSocket With Traditional Methods
Journal of New Results in Science, 2016 The Internet has become an indispensable part of human life in the rapidly growing information age. In response to this demand the number of web-based applications is increasing as well.
Onur Cömert, Mahmut Hekim, Kemal Adem
doaj
Environmental and Molecular Mutagenesis, EarlyView.Abstract Gene expression biomarkers have the potential to identify genotoxic and non‐genotoxic carcinogens, providing opportunities for integrated testing and reducing animal use. In August 2022, an International Workshops on Genotoxicity Testing (IWGT) workshop was held to critically review current methods to identify genotoxicants using ...
Roland Froetschl +14 more
wiley +1 more source
The gas production rate of periodic comet d'Arrest [PDF]
Comet P/d'Arrest is a potential target for a rendezvous mission to a short period comet. Its light curve is rather peculiar, the comet being active only after perihelion passage. One apparition out of two is easy to observe from the ground.
Ahearn, Michael F. +2 more
core +1 more source
Single cell gel/comet assay: Guidelines for in vitro and in vivo genetic toxicology testing
Environmental and Molecular Mutagenesis, 2000 R. Tice +9 more
semanticscholar +1 more source
Review of Transcriptomic Biomarkers That Predict In Vitro Genotoxicity in Human Cell Lines
Environmental and Molecular Mutagenesis, EarlyView.ABSTRACT The current genotoxicity testing paradigm provides little mechanistic information, has poor specificity in predicting carcinogenicity in humans, and is not suited to assessing a large number of chemicals. Genomic technologies enable the characterization of genome‐wide transcriptional changes in response to chemical treatments that can inform ...
Heng‐Hong Li +7 more
wiley +1 more source