Results 191 to 200 of about 81,496 (301)

A machine learning approach to leveraging electronic health records for enhanced omics analysis. [PDF]

open access: yesNat Mach Intell
Mataraso SJ   +19 more
europepmc   +1 more source

ATR Inhibition Synergizes With Alkylating PI Polyamide Targeting MYCN by Suppressing DNA Repair in MYCN‐Amplified Neuroblastoma

open access: yesCancer Science, EarlyView.
We found that among the DNA damage response inhibitors, ataxia telangiectasia and Rad3‐related (ATR) inhibitors synergized with CCC‐002 to suppress DNA repair‐related genes and induce apoptosis in MYCN‐amp neuroblastoma cells. These findings suggest that the combination of ATR inhibition and CCC‐002 is highly effective against MYCN‐amp neuroblastomas ...
Xiaoyi Lai   +7 more
wiley   +1 more source

Combinatorial mapping of E3 ubiquitin ligases to their target substrates. [PDF]

open access: yesMol Cell
Suiter CC   +10 more
europepmc   +1 more source

Morehouse's Comet [PDF]

open access: green, 1908
Edwin B. Frost
openalex   +1 more source

Comet Notes [PDF]

open access: yesPublications of the Astronomical Society of the Pacific, 1951
openaire   +3 more sources

Changing Our Mental and Emotional Trajectory (COMET): The Feasibility and Acceptability of a Rural Community-Based Strategy to Prevent Mental and Emotional Health Problems. [PDF]

open access: yesJ Prim Care Community Health
Zittleman L   +8 more
europepmc   +1 more source

The Dual Roles of Lamin A/C in Macrophage Mechanotransduction

open access: yesCell Proliferation, EarlyView.
Compressive force can inhibit the expression of lamin A/C, SUN1 and SUN2 in macrophages. Lamin A deficiency may participate in mechanotransduction within macrophages through two distinct mechanisms. ABSTRACT Cellular mechanotransduction is a complex physiological process that integrates alterations in the external environment with cellular behaviours ...
Yao Wang   +5 more
wiley   +1 more source

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