Results 261 to 270 of about 291,896 (358)

What can lithics tell us about food production during the transition to farming? Exploring harvesting practices and cultural changes during the neolithic in Southwest Asia: a view from Qminas (north‐western Syria)

open access: yesArchaeometry, EarlyView.
Abstract This study examines the continuity and change in harvesting practices between the Late Pre‐Pottery Neolithic B (LPPNB) and the Early Pottery Neolithic at Qminas, north‐western Levant, through a traceological analysis of flint sickles. By combining qualitative traceological analysis with quantitative functional approaches, we demonstrate that ...
Fiona Pichon   +3 more
wiley   +1 more source

Evaluating DNA damage in earthworms (Eisenia fetida's): toxicological insights from carbon, gold, and silver nanoparticles using enzyme and comet assays. [PDF]

open access: yesBMC Chem
Latif R   +9 more
europepmc   +1 more source

cGAS–STING Pathway Activation Enhances Antitumor Effect of Talaporfin Photodynamic Therapy Through ROS Production

open access: yesCancer Science, EarlyView.
This study investigates the role of STING in photodynamic therapy (PDT) using talaporfin sodium. STING knockout reduced ROS generation and therapeutic efficacy, while combining a STING agonist with PDT enhanced antitumor effects. These findings suggest that STING regulates ROS homeostasis and can potentiate PDT outcomes.
Makiko Sasaki   +11 more
wiley   +1 more source

Elucidating the Role and Mechanism of Alpha‐Enolase in Senescent Amelioration via Metabolic Reprogramming

open access: yesCell Proliferation, EarlyView.
KB2764 interacted with alpha‐enolase (ENO1) and pyruvate kinase M (PKM), ultimately leading to PKM phosphorylation of ENO1. KB2764 consequently increased mitochondrial ATP production and decreased glycolysis dependence. Furthermore, the action of KB2764 extends its application to extend the lifespan of Caenorhabditis elegans.
Yun Haeng Lee   +13 more
wiley   +1 more source

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