Results 261 to 270 of about 225,144 (339)
DNA damage can cause mitotic delay to allow DNA repair to occur. However, the mechanism underlying this is unclear. Here, we show that in response to cells entering mitosis with DNA damage, SOD1 restrains PP2a activity via oxidation of cysteine residues at the active site. This leads to a reduction in PP2a activity at the mitotic kinetochore, resulting
Nan Li+7 more
wiley +1 more source
Bioactivity of mycosynthesized nanoparticles assists photothermal therapy of breast cancer cells. [PDF]
Ezzat A, Ramadan MA, Eid JI, Ahmed OS.
europepmc +1 more source
Activation of CLIP170 by CDKL5 in wild‐type (WT) cells promotes its open conformation and association with tyrosinated microtubule (MT) plus‐ends (+), where it works as a docking site to recruit the dynactin–dynein–cargo complex, promoting the initiation of retrograde transport. In knock‐out (KO) neurons, CLIP170 is mainly present in a closed (inactive)
Serena Baldin+4 more
wiley +1 more source
DNA damage in oral mucosal epithelial cells cultured in complex and xenobiotic-free media: a comparison study. [PDF]
Cabral JV+8 more
europepmc +1 more source
ABSTRACT Aims To explore how older adult‐family caregiver dyads jointly manage multiple chronic conditions. Specifically, it investigates how dyads (i) prioritise chronic diseases, (ii) make and negotiate decisions related to self‐care and (iii) define and distribute self‐care tasks and caregiver contributions.
Giulia Andrea Baldan+6 more
wiley +1 more source