Results 271 to 280 of about 291,896 (358)
RBM39 Promotes Base Excision Repair to Facilitate the Progression of HCC by Stabilising OGG1 mRNA
Targeting RBM39 attenuates BER via destabilising OGG1 mRNA and potentiates KBrO3‐induced oxidative stress in HCC. Our study represents a valuable treatment strategy combining indisulam and an oxidative stress inducer in HCC. ABSTRACT Targeting base excision repair (BER) has been an attractive strategy in cancer therapeutics.
Hongda An+7 more
wiley +1 more source
FLASH-induced DNA damage reduction measured in vitro correlates with effective oxygen depletion determined in silico: further support for oxygen depletion contributing to FLASH's reduced damage burden in vitro. [PDF]
Rothwell B+8 more
europepmc +1 more source
The organic-rich surface of comet 67P/Churyumov-Gerasimenko as seen by VIRTIS/Rosetta
F. Capaccioni+79 more
semanticscholar +1 more source
Intervenções de esportes modificados para crianças com Paralisia Cerebral: Resumo gráfico. Resumo Objetivo Avaliar a eficácia de uma intervenção de esportes modificados (Sports Stars Brasil) nos objetivos de participação em atividades físicas de lazer, desempenho e capacidade motora, funções corporais, níveis de atividade física, alfabetização física e
Ricardo R. Sousa Junior+7 more
wiley +1 more source
Targeting ESKAPE pathogens with ZnS and Au@ZnS Core-Shell nanoconjugates for improved biofilm control. [PDF]
Ibrahim SI+7 more
europepmc +1 more source
Abstract At present, the outcomes measured and reported in clinical trials for adults with epilepsy are heterogenous and have often not been selected in consultation with people living with epilepsy. As part of a wider project developing a core outcome set for clinical trials for adults with epilepsy (the EPSET Project), a rapid review of the published
James W. Mitchell+4 more
wiley +1 more source
Slightly increased level of DNA migration in the comet assay: does statistical significance equal biological significance? [PDF]
Møller P+5 more
europepmc +1 more source
DNA damage can cause mitotic delay to allow DNA repair to occur. However, the mechanism underlying this is unclear. Here, we show that in response to cells entering mitosis with DNA damage, SOD1 restrains PP2a activity via oxidation of cysteine residues at the active site. This leads to a reduction in PP2a activity at the mitotic kinetochore, resulting
Nan Li+7 more
wiley +1 more source