Results 271 to 280 of about 81,496 (301)

Bruceine A Inhibits Cell Proliferation by Targeting the USP13/PARP1 Signalling Pathway in Multiple Myeloma

open access: yesBasic &Clinical Pharmacology &Toxicology, Volume 136, Issue 5, May 2025.
USP13 is a promising therapeutic target for cellular proliferation in multiple myeloma. Bruceine A can retard the development of multiple myeloma by targeting USP13/PARP1‐mediated DNA damage repair and triggering cell apoptosis. ABSTRACT Multiple myeloma (MM) is an incurable hematologic malignancy, driving significant interest in the discovery of novel
Mengjie Guo   +9 more
wiley   +1 more source

Comparative evaluation of autologous tissue-engineered ocular and oral mucosal tissue grafts- a prospective randomized controlled trial. [PDF]

open access: yesBMC Biotechnol
Tandon R   +11 more
europepmc   +1 more source

Policy and practice recommendations for services for disabled children during emergencies: Learning from COVID‐19

open access: yesDevelopmental Medicine &Child Neurology, Volume 67, Issue 5, Page 676-687, May 2025.
This original article is commented by Hindi on pages 561–562 of this issue. Abstract Aim To seek consensus on recommendations for the delivery of services to disabled children in England during future emergencies. Method Candidate recommendations were drafted based on our related mapping review and qualitative research related to experiences during the
Hannah Merrick   +14 more
wiley   +1 more source

Ranibizumab with luseogliflozin in type 2 diabetes with diabetic macular oedema: A randomised clinical trial

open access: yesDiabetes, Obesity and Metabolism, Volume 27, Issue 5, Page 2473-2484, May 2025.
Abstract Aims Anti‐vascular endothelial growth factor (VEGF) therapy is the standard treatment for diabetic macular oedema (DMO); however, unmet needs remain. This study aimed to assess the effectiveness of sodium‐glucose cotransporter 2 inhibitors (SGLT2i) in treating DMO.
Ryoichi Ishibashi   +12 more
wiley   +1 more source

New advanced models (NAMs) for risk assessment of bisphenol A alternatives. [PDF]

open access: yesEFSA J
Honza T   +4 more
europepmc   +1 more source

Assessing brain neuroplasticity: Surface morphometric analysis of cortical changes induced by Quadrato motor training

open access: yesJournal of Anatomy, Volume 246, Issue 5, Page 757-769, May 2025.
Morphological markers for brain plasticity are still lacking, and their findings are challenged by cortical brain surface variability. To overcome the “correspondence problem,” we used a landmark‐free method (generalized Procrustes surface analysis, GPSA) to investigate cortical surface shape variation in healthy volunteers practicing Quadrato motor ...
F. Spani   +5 more
wiley   +1 more source

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