Results 121 to 130 of about 9,305 (228)

Synergistic RU486 and olaparib therapy enhances apoptosis in endometriosis by simultaneously targeting hormonal signalling and DNA repair

British Journal of Pharmacology, Volume 183, Issue 11, Page 2947-2968, June 2026.
Background and Purpose Endometriosis is a chronic, hormone‐dependent disorder characterized by ectopic implantation of endometrial tissue, often accompanied by pain and infertility. Although the progesterone receptor modulator RU486 is effective for pain relief, its impact on lesion regression is limited, possibly due to apoptosis resistance and ...
Yujie Peng, Meng Zhang, Libo Zhu, Wenqiang Qian, Jingjing Yan, Huidi Jiang, Yu Xin, Ying Zhang, Dongli Sun, Weidong Fei, Mengdan Zhao   +10 more
wiley   +1 more source

Strength of comet material and Hertzian contact-mechanics applied to the landing of Philae on comet Churyumov-Gerasimenko

, 2009
We estimate the strength of cometary material using fracture mechanics and regarding the comet material as a green "ceramic" body. The breakage strength Y is estimated using the fracture strength of ceramic slurries, so-called green bodies, and is ...
Arnold, W., Möhlmann, D.
core  

Anhydrous minerals in asteroid Bennu: Evidence for well‐preserved primordial components

Meteoritics &Planetary Science, Volume 61, Issue 6, Page 963-986, June 2026.
Abstract Aqueously altered carbonaceous astromaterials are dominated by secondary minerals, but a minor fraction of primary, anhydrous silicates and oxides escape alteration, offering insight into the original composition of asteroid parent bodies. We report the mineralogy, petrology, mineral chemistry, and oxygen isotopes of anhydrous minerals—50 ...
S. S. Russell, I. A. Franchi, T. Salge, X. Zhao, R. H. Jones, A. J. King, N. V. Almeida, P. F. Schofield, H. C. Bates, E. A. Cortes‐Calderon, N. Kawasaki, Y. Yurimoto, Y. Marrocchi, G. Libourel, K. Thomas‐Keprta, L. P. Keller, K. Righter, T. J. McCoy, T. J. Zega, J. J. Barnes, A. N. Nguyen, S. Tachibana, H. C. Connolly Jr, D. S. Lauretta   +23 more
wiley   +1 more source

Miniaturizing the comet assay with 3D vertical comets

, 2002
Background: The comet or single-cell gel electrophoresis assay is a sensitive method for the detection of DNA damage. The main drawback of comet sampling is the low cell density necessary to prevent nucleus overlap after electrophoresis, which limits ...
Patrick Van Oostveldt, Philippe Baert, Van Oostveldt, Patric, Baert, Philippe   +3 more
core   +1 more source

Chaotic dynamics around cometary nuclei

, 2018
International audienceWe apply a generalized Kepler map theory to describe the qualitative chaotic dynamics around cometary nuclei, based on accessible observational data for five comets whose nuclei are well-documented to resemble dumb-bells.
Rollin, Guillaume, Guillaume Rollin, José Lages, Ivan I. Shevchenko, Lages, José, Shevchenko, Ivan I.   +5 more
core   +1 more source

Investigating Local- and Global-scale Dust Redistribution on Comet 67P/Churyumov–Gerasimenko

The Planetary Science Journal
We use a 3D dynamical Monte Carlo model to simulate the trajectories of individual dust grains and map their redeposition across the surface of comet 67P/Churyumov–Gerasimenko.
Jacob L. Kloos, Tony L. Farnham, Jessica M. Sunshine, Juan Luis Rizos   +3 more
doaj   +1 more source

Estimates of DNA damage by the comet assay in the direct-developing frog Eleutherodactylus johnstonei (Anura, Eleutherodactylidae)

Genetics and Molecular Biology, 2011
The aim of this study was to use the Comet assay to assess genetic damage in the direct-developing frog Eleutherodactylus johnstonei. A DNA diffusion assay was used to evaluate the effectiveness of alkaline, enzymatic and alkaline/enzymatic treatments ...
Laura Carolina Valencia, Adriana García, Martha Patricia Ramírez-Pinilla, Jorge Luis Fuentes   +3 more
doaj  

Predictions for Sparse Photometry of Jupiter-family Comet Nuclei in the LSST Era

The Planetary Science Journal
The Legacy Survey of Space and Time (LSST) at Vera C. Rubin Observatory will deliver high-quality, temporally sparse observations of millions of solar system objects on an unprecedented scale.
A. Donaldson, C. Snodgrass, R. Kokotanekova, A. Rożek   +3 more
doaj   +1 more source

A search for the source of short-period comet nuclei. The direction of spatial comet migration

, 2012
Предпринята попытка установить пространственное расположение главного источника ядер короткопериодических комет. На основании численных расчетов эволюции орбит комет семейства Юпитера, средне периодических комет и тел группы Кентавров показано, что ...
Казанцев А.М.
core   +1 more source

Modelling of the gas dynamics in the inner-coma and the composition of comet 67P/Churyumov-Gerasimenko

, 2021
This thesis presents a study of the gas dynamics of cometary nuclei with a focus on the target of the Rosetta mission, comet 67P/Churyumov-Gerasimenko. We therefore apply the 3D Direct Simulation Monte Carlo (DSMC) method to different distributions of ...
Pinzón Rodriguez, Olga Janeth
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