Results 101 to 110 of about 9,305 (228)
Reversal of Spin: Comet 41P/Tuttle–Giacobini–Kresak
The rotations of cometary nuclei are known to change in response to outgassing torques. The nucleus of the Jupiter-family comet 41P/Tuttle–Giacobini–Kresak exhibited particularly dramatic rotational changes when near perihelion in 2017 April.
David Jewitt
doaj +1 more source
Lung cancer remains the leading cause of cancer‐related death. We investigated the role of the epigenetic regulator DMAP1 in NSCLC and found that its loss induces replication stress and DNA damage. This in turn activates type I IFN signaling via the cGAS–STING pathway and transcriptional ISG de‐repression, enhancing anti‐tumor immune responses ...
Kan Huang +10 more
wiley +1 more source
Analytical study of comet nucleus samples
Analytical procedures for studying and handling frozen (130 K) core samples of comet nuclei are discussed. These methods include neutron activation analysis, x ray fluorescent analysis and high resolution mass ...
Albee, A. L.
core
Macrophage Extracellular Traps in Immunity and Cancer
As a macrophage‐mediated innate defense mechanism, the dysregulated release of METs drives chronic inflammation and influences tumor progression. Furthermore, METs exhibit a functional duality within the tumor microenvironment, capable of both promoting and suppressing tumor development.
Junyao Li +5 more
wiley +1 more source
The past year was one of tremendous activity because of the appearance of Halley's Comet. Observations of the comet were collected from a number of sources and compared with the detailed predictions of the comet thermal modeling program.
Weissman, Paul R., Kieffer, Hugh H.
core
Comet geology with Deep Impact remote sensing
. The Deep Impact mission will provide the highest resolution images yet of a comet nucleus. Our knowledge of the makeup and structure of cometary nuclei, and the processes shaping their surfaces, is extremely limited, thus use of the Deep Impact data to
Peter C. Thomas +5 more
core +1 more source
Case Report: Synchronous Manifestations of Kaposi Sarcoma Herpesvirus‐Associated Disorders
ABSTRACT Background Kaposi sarcoma herpes virus (KSHV) is associated with multiple clinical manifestations, including primary effusion lymphoma, an aggressive CD38+ B cell lymphoma with a plasmablastic phenotype. Case This case describes an antiretroviral therapy‐adherent person with HIV who presented with concurrent KSHV‐related disorders of Kaposi ...
Kandice Roberts +13 more
wiley +1 more source
The JaCVAM / OECD activities on the comet assay
The in vivo alkaline single cell gel electrophoresis assay, also called alkaline comet assay is a method measuring DNA strand breaks in eukaryotic cells.
Hajime Kojima
doaj +1 more source
Physical Properties of Frozen Volatiles—Their Relevance to the Study of Comet Nuclei [PDF]
AbstractThe structural and thermodynamical properties of water ice and ice mixtures containing CO, CO2, CH4, and NH3 are thought to be important for the evolution of cometary nuclei. Based on recent laboratory studies performed by several groups, an overview is given of the properties of various ices condensed at low temperatures and of their evolution
openaire +1 more source
Lamin B1 safeguards the B cell genome and shapes lymphoma outcome
Abstract Lamin B1 is a structural component of the nuclear lamina that participates in genome organization and transcriptional control. During adaptive immune responses, B lymphocytes in germinal centers (GCs) undergo clonal expansion and programmed DNA damage at immunoglobulin loci, while simultaneously downregulating Lamin B1.
Filip Filipsky +12 more
wiley +1 more source

