Results 91 to 100 of about 329,629 (202)

Understanding extracellular vesicles in antiaging

Periodontology 2000, EarlyView.
Abstract Background Aging is a multifactorial process marked by gradual cellular dysregulation, regulated by hallmarks, including genomic instability, mitochondrial dysregulation, and chronic inflammation. Extracellular vesicles (EVs), especially exosomes, have emerged as pivotal mediators of cell‐to‐cell communication with potential roles in both ...
Paras Ahmad, Nathan E. Estrin, Anton Sculean, Richard J. Miron   +3 more
wiley   +1 more source

The alkaline comet assay used in evaluation of genotoxic damage of drinking water disinfection by-products (bromoform and chloroform)

Frontiers in Genetics, 2015
The alkaline comet assay (pH 12.3) is a useful method for monitoring genotoxic effects of environmental pollutants in the root nuclei of Allium cepa and various plants; it allows the detection of single- and double-strand breaks, incomplete excision ...
Messaouda Khallef, Recep Liman, İbrahim Hakkı Ciğerci, Muhsin Konuk   +3 more
doaj   +1 more source

A Müller Glia‐Retinal Pigment Epithelium Apical Network Surrounding Cone Outer Segments in Fish and Mouse

Glia, Volume 74, Issue 12, December 2026.
Müller glia and the retinal pigment epithelium interact around cone outer segment in the subretinal space of both zebrafish and mouse. The contacts are established early during development but subsequent to outer segment emergence. ABSTRACT Homeostasis of the vertebrate retina critically depends on two non‐neuronal cell populations, Müller glia and the
Maria Sharkova, Michael Housset, Samantha Boudreau, Chavy Dworkind, Sara Amidian, Michel Cayouette, Jennifer C. Hocking   +6 more
wiley   +1 more source

Polyglycine Strands Within a Collagen Triple Helix

Biopolymers, Volume 117, Issue 6, November 2026.
ABSTRACT The collagen triple helix is the most abundant protein structural motif in animals. It tolerates any amino acid in its Xaa and Yaa positions but demands glycine (Gly) at every third position, where the residue packs into the sterically forbidding core of the triple helix and donates the recurring interstrand N–H⋯OC hydrogen bond that stitches
Wasin Tiarawut, Gabriel Saenz, Jinyi Yang, Ronald T. Raines   +3 more
wiley   +1 more source

Nucleus and Postperihelion Activity of Interstellar Object 3I/ATLAS Observed by the Hubble Space Telescope

The Astrophysical Journal Letters
We report the detection of the nucleus of interstellar object 3I/ATLAS, using a nucleus extraction technique on Hubble Space Telescope (HST) observations taken between 2025 December and 2026 January.
Man-To Hui, David Jewitt, Max J. Mutchler, Jessica Agarwal, Yoonyoung Kim   +4 more
doaj   +1 more source

The nature of comet-asteroid transition object (3200) Phaethon

, 2006
Context. The study of asteroids that present sporadic cometary activity is of fundamental importance to address several astronomical problems including the end states of comet nuclei, the abundance of water in main belt asteroids, and its role as a ...
Pinilla-Alonso, N., T. Mothé-Diniz, H. Campins, Campins, H., J. Licandro, De León, J., J. de León, Licandro, J., N. Pinilla-Alonso, Mothé-Diniz, T.   +9 more
core   +2 more sources

Evaluation of DNA/Chromosome Integrity and Cell Death in Human Metabolically Noncompetent and Competent Cells Exposed to N′‐(3,5‐Difluorobenzylidene)Pyridine‐4‐Carbohydrazide

Journal of Applied Toxicology, Volume 46, Issue 11, Page 4076-4084, November 2026.
ABSTRACT The N‐acylhydrazone scaffold is recognized as a privileged structure for the design of bioactive substances with increasing applications in medicinal chemistry research. Ensuring the safety of newly developed molecules is a critical step for both human health and environmental protection. Accordingly, this study aimed to evaluate the cytotoxic
Larissa Ribeiro Canuto Santos, Jéssica Natalia Barbosa de Almeida, Camila Cavalleiro Frias, Wanda Pereira Almeida, Edson Luis Maistro   +4 more
wiley   +1 more source

Implications of the Small Spin Changes Measured for Large Jupiter-Family Comet Nuclei [PDF]

, 2018
Rotational spin-up due to outgassing of comet nuclei has been identified as a possible mechanism for considerable mass-loss and splitting. We report a search for spin changes for three large Jupiter-family comets (JFCs): 14P/Wolf, 143P/Kowal-Mrkos, and ...
Green, S., Bonev, T., P Lacerda, Kokotanekova, R., Nikolov, P., R Kokotanekova, Lacerda, P., P Nikolov, C Snodgrass, T Bonev, Green, S. F., Snodgrass, C., S F Green   +12 more
core   +1 more source

Micronuclei and Other Nuclear Abnormalities in Patella Limpet as Biomarkers of Cytogenotoxicity in Recreational Port Waters

Environmental Toxicology, Volume 41, Issue 11, Page 1125-1138, November 2026.
ABSTRACT Over the past decades, the growth in human population and economic activities has led to an increase in maritime traffic. This rise puts additional pressure on marine environments, vessel fuel spills being considered to have a major impact on the ecosystem.
Carlos Valiente‐Diaz, Eva Garcia‐Vazquez, Verónica Soto‐López   +2 more
wiley   +1 more source

On the Early Thermal Processing of Planetesimals during and after the Giant Planet Instability

The Planetary Science Journal
Born as ice-rich planetesimals, cometary nuclei were gravitationally scattered onto their current orbits in the Kuiper Belt and the Oort Cloud during the giant planets’ dynamical instability in the early stages of our solar system’s history.
Anastasios Gkotsinas, David Nesvorný, Aurélie Guilbert-Lepoutre, Sean N. Raymond, Nathan Kaib   +4 more
doaj   +1 more source