Results 81 to 90 of about 312,980 (227)

Contemporaneous Optical and Near-infrared Observations of the Interstellar Comet 3I/ATLAS Pre- and Postperihelion

The Astronomical Journal
Interstellar objects provide a unique view into the formation of other star systems. Here we present spectroscopic observations of the recently discovered interstellar object 3I/ATLAS between a heliocentric distance of 3.7–1.8 au on either side of its ...
Kyle Medler, Willem B. Hoogendam, Christopher Ashall, Bin Yang, James J. Wray, Benjamin J. Shappee, Karen J. Meech, Michael A. Tucker, Katie Auchettl, Dhvanil D. Desai, Jason T. Hinkle, Andrew M. Hoffman, Mark E. Huber, David O. Jones, Ruining Zhao   +14 more
doaj   +1 more source

NTAQ1 Promotes Hepatocellular Carcinoma Growth by Facilitating the Protein Degradation of the Tumor Suppressor PRDM2

Cancer Science, EarlyView.
Copy number variation analysis in The Cancer Genome Atlas identified NTAQ1 as a potential driver of HCC progression. NTAQ1 accelerates tumor growth by promoting the degradation of the tumor suppressor protein PRDM2, thereby impairing DNA repair and suppressing apoptosis. These findings indicate that NTAQ1 could be a valuable target for the treatment of
Tomohiko Ikehara, Hajime Otsu, Taro Tobo, Kiyotaka Hosoda, Tadashi Abe, Masahiro Hashimoto, Yusuke Nakano, Katsushi Dairaku, Yuya Ono, Yuki Miyata, Chihiro Matsumoto, Takanari Tatsumi, Satoshi Higuchi, Takashi Ofuchi, Akinori Tsujimoto, Yuki Ando, Qingjiang Hu, Yusuke Yonemura, Akira Shimizu, Takaaki Masuda, Yuji Soejima, Koshi Mimori   +21 more
wiley   +1 more source

Optimization of Neutral Comet Assay for studying DNA double-strand breaks in pea and wheat [PDF]

Journal of BioScience and Biotechnology, 2013
This study describes an adaptation of the Comet assay under neutral conditions for mono- and dicotyledonous plants pea (Pisum sativum L.) and wheat (Triticum aestivum L.).
Ivelina Nikolova, Mariyana Georgieva, Lubomir Stoilov, Zornica Katerova, Desisslava Todorova   +4 more
doaj  

RFP for the Comet Nuclei Tour (CONTOUR)

, 1999
This document describes the ASC Star Tracker (performance, functionality, requirements etc.) to The Johns Hopkins University - Applied Physics Laboratory for their Comet Nuclei TOUR (CONTOUR ...
Thuesen, Gøsta, Kilsgaard, Søren, Betto, Maurizio, Jørgensen, Finn E, Denver, Troelz, Jørgensen, John Leif, Madsen, Peter Buch, Riis, Troels   +7 more
core  

Intervention outcomes of children with non‐degenerative dystonia and associated hyperkinetic movement disorders: A scoping review

Developmental Medicine &Child Neurology, EarlyView.
Abstract Aim To identify the outcomes reported in published studies of intervention approaches used with non‐degenerative childhood hyperkinetic movement disorders, including dystonia, dyskinesia, hypertonia, athetosis, chorea, cerebral palsy, involuntary movement, and kernicterus, and map them to the International Classification of Functioning ...
Hortensia Gimeno, Hannah Scott, Rocio Muñoz Sanchez, Alice Doohan, Deepti Chugh, Adrienne Harvey, Kirsty Stewart, Peter Rosenbaum, Grace Stynes, Khamani Edwards, Katherine Knighting   +10 more
wiley   +1 more source

Compromised DNA replication in gut cells underlies sensitivity to genotoxic stress in the tardigrade Hypsibius exemplaris

The FEBS Journal, EarlyView.
DNA damage in the tardigrade Hypsibius exemplaris elicits distinct cellular outcomes depending on replication status. While non‐replicating cells tolerate genotoxic stress, constitutively replicating cells undergo irreversible replication failure upon DNA damage, leading to loss of tissue homeostasis, fat depletion, sterility, and organismal death ...
Gonzalo Quiroga‐Artigas, Pauline Fontanié, Benjamin Lacroix, Maria Dolores Molina, María Moriel‐Carretero   +4 more
wiley   +1 more source

Down But Not Out: The Case of Long-period Comet C/2021 O3 (Panstarrs)

The Astronomical Journal
We combine ground- and space-based observations of long-period comet C/2021 O3 (Panstarrs; perihelion distance 0.287 au) in order to investigate its reported near-perihelion destruction.
David Jewitt, Jing Li, Michael Jaeger, Yoonyoung Kim   +3 more
doaj   +1 more source

Potato virus X induces DNA damage in leaf nuclei of the host plant Nicotiana tabacum L. var. xanthi

Biologia Plantarum, 2014
We employed the comet assay (single cell gel electrophoresis) to evaluate induced DNA damage in nuclei isolated from tobacco leaves (Nicotiana tabacum var. xanthi) inoculated with Potato virus X (PVX). The highest DNA damage, expressed by the tail moment
N. Cerovska, H. Plchova, P. Vaculik, T. Moravec, T. Gichner   +4 more
doaj   +1 more source

3SD: Rotational symmetry single‐shot denoising in fluorescence microscopy

Journal of Microscopy, EarlyView.
Abstract Image noise is a fundamental problem in fluorescence microscopy analysis, especially in live cell imaging applications where the number of detected photons is limited due to low power of excitation lasers to prevent phototoxicity during extended imaging experiments.
Tijmen H. de Wolf, Pleun Engbers, Justine Perrin, Julie Nonnekens, Ihor Smal   +4 more
wiley   +1 more source

The alkaline comet assay used in evaluation of genotoxic damage of drinking water disinfection by-products (bromoform and chloroform)

Frontiers in Genetics, 2015
The alkaline comet assay (pH 12.3) is a useful method for monitoring genotoxic effects of environmental pollutants in the root nuclei of Allium cepa and various plants; it allows the detection of single- and double-strand breaks, incomplete excision ...
Messaouda Khallef, Recep Liman, İbrahim Hakkı Ciğerci, Muhsin Konuk   +3 more
doaj   +1 more source