Results 61 to 70 of about 549,270 (251)
Journal of Applied Toxicology, EarlyView.ABSTRACT The N‐acylhydrazone scaffold is recognized as a privileged structure for the design of bioactive substances with increasing applications in medicinal chemistry research. Ensuring the safety of newly developed molecules is a critical step for both human health and environmental protection. Accordingly, this study aimed to evaluate the cytotoxic
Larissa Ribeiro Canuto Santos +4 more
wiley +1 more source
Evaluation of genetic damage induced by glyphosate isopropylamine salt using Tradescantia bioassays
Genetics and Molecular Biology, 2011 Glyphosate is noted for being non-toxic in fishes, birds and mammals (including humans). Nevertheless, the degree of genotoxicity is seriously controversial.
Carlos Alvarez-Moya +5 more
doaj
Modified comet assays for the detection of cyclobutane pyrimidine dimers and oxidative base damages
Journal of Radiation and Cancer Research, 2017 The comet assay (also known as single-cell gel electrophoresis) is a technique for the detection of DNA damage at the level of the individual cell. It is a versatile, relatively simple to perform and sensitive method.
Ganesan Muthusamy +6 more
doaj +1 more source
FUV Observations of the Inner Coma of 46P/Wirtanen
The Planetary Science Journal, 2021 Far-ultraviolet observations of comets yield information about the energetic processes that dissociate the sublimated gases from their primitive surfaces.
John W. Noonan +8 more
doaj +1 more source
Comet C/2004 Q2 (MACHHOLZ): Parent Volatiles, a Search for Deuterated Methane, and Constraint on the CH4 Spin Temperature [PDF]
, 2009 High-dispersion (l/dl ~ 25,000) infrared spectra of Comet C/2004 Q2 (Machholz) were acquired on Nov. 28-29, 2004, and Jan. 19, 2005 (UT dates) with NIRSPEC at the Keck-2 telescope on Mauna Kea.
Aikawa +43 more
core +2 more sources
Deubiquitinase USP38 Stabilizes PLK1 Expression to Boost DNA Damage Repair in Ovarian Cancer
The Kaohsiung Journal of Medical Sciences, EarlyView.ABSTRACT Ovarian cancer (OC) is one of the most prevalent and severe gynecological malignant tumors. DNA damage repair (DDR) is essential in maintaining genome stability. This study aims to investigate the effects and mechanisms of USP38 and PLK1 on DNA damage repair and malignant behavior in OC cells.
Yuan Ma, Ying Li, Kai‐Li Li
wiley +1 more source
NSF-DOE Vera C. Rubin Observatory Observations of Interstellar Comet 3I/ATLAS (C/2025 N1)
The Astrophysical Journal LettersWe report on the observation and measurement of astrometry, photometry, morphology, and activity of the interstellar object 3I/ATLAS, also designated C/2025 N1 (ATLAS) with the NSF-DOE Vera C. Rubin Observatory.
Colin Orion Chandler +305 more
doaj +1 more source
Physics Letters B, 2017 The experimental sensitivity to μ→e conversion on nuclei is expected to improve by four orders of magnitude in coming years. We consider the impact of μ→e flavour-changing tensor and axial-vector four-fermion operators which couple to the spin of ...
Vincenzo Cirigliano +2 more
doaj +1 more source
Formation of bi-lobed shapes by sub-catastrophic collisions: A late origin of comet 67P/C-G's structure [PDF]
, 2016 The origin of the particular shape of a small body like comet 67P/Churyumov-Gerasimenko (67P/C-G) is a topic of active research. How and when it acquired its peculiar characteristics has distinct implications on the origin of the solar system and its ...
Benz, W., Jutzi, M.
core +2 more sources
Environmental Toxicology, EarlyView.ABSTRACT This study reports, for the first time, the use of the speckled cockroach Nauphoeta cinerea as a promising bioindicator for genotoxic monitoring. It was validated through control groups (both positive and negative) in addition to testing lettuce (Lactuca sativa ) samples from public street markets consumed by N. cinerea specimens in Pernambuco,
Aleson Aparecido da Silva +4 more
wiley +1 more source