Results 41 to 50 of about 549,270 (251)
Advanced Science, EarlyView.Pancreatic neuroendocrine tumors frequently silence MEN1 through epigenetic mechanisms. Here, SIRT7 recruits DNMT1 to the MEN1 promoter, drives hypermethylation, and enhances DNA repair. Inhibiting SIRT7 restores MEN1, reduces MRN complex abundance, impairs double‐strand break repair, and sensitizes PanNET models to radiation, supporting SIRT7 as a ...
Jianyun Jiang +11 more
wiley +1 more source
The Planetary Science JournalComets, as remnants of the solar system’s formation, vary in volatile-refractory content. In situ comet studies, such as the Rosetta mission to 67P/Churyumov–Gerasimenko, provide detailed volatile composition insights, while ground-based studies offer ...
Mohammad Saki +7 more
doaj +1 more source
Evaluation of the genotoxicity of some standart and eco-friendly detergents with Vicia faba
Caryologia, 2021 The increasing use of detergents as a result of rapid increase of population and irregular industrialization has a big role in the environmental pollution.
Özlem Aksoy, Aylin Horozal
doaj +1 more source
Impact of sterile neutrinos on nuclear-assisted cLFV processes [PDF]
, 2016 We discuss charged lepton flavour violating processes occurring in the presence of muonic atoms, such as muon-electron conversion in nuclei $\text{CR}(\mu -e, \text{ N})$, the (Coulomb enhanced) decay of muonic atoms into a pair of electrons BR($\mu^- e^-
Abada, A. +2 more
core +6 more sources
Ground-based Support of Comet Nuclei Space Missions [PDF]
Symposium - International Astronomical Union, 2004 There are currently five space missions en route to or planned for comet encounters. It is important for the success of each mission that its target be characterized as fully as possible prior to the encounter. This progress report analyses initial photometric results for 11 comet nuclei for the Stardust, Rosetta, Deep Impact, CONTOUR, Deep Space 1 ...
Jana Pittichová, Karen J. Meech
openaire +1 more source
Detection of comet nuclei at large heliocentric distances [PDF]
Monthly Notices of the Royal Astronomical Society, 1992 The largest long-period comets which have passed perihelion during the past half-century should still be observable. Fourteen candidate comets with well-determined orbits are presented, including data on their absolute magnitudes, distances and predicted positions in the sky.
M. E. Bailey, J. E. Chambers, G. Hahn
openaire +1 more source
Macrophage Extracellular Traps in Immunity and Cancer
Advanced Science, EarlyView.As a macrophage‐mediated innate defense mechanism, the dysregulated release of METs drives chronic inflammation and influences tumor progression. Furthermore, METs exhibit a functional duality within the tumor microenvironment, capable of both promoting and suppressing tumor development.
Junyao Li +5 more
wiley +1 more source
Redistribution of DNA loop domains in human lymphocytes under blast transformation with interleukin 2 [PDF]
The Ukrainian Biochemical Journal, 2016 At higher order levels chromatin fibers in interphase nuclei are organized into loop domains. Gene regulatory elements (promoters and enhancers) are often located near the sites of loop attachments.
K. S. Afanasieva +4 more
doaj +1 more source
Albedos of Main-Belt Comets 133P/Elst-Pizarro and 176P/LINEAR [PDF]
, 2009 We present the determination of the geometric R-band albedos of two main-belt comet nuclei based on data from the Spitzer Space Telescope and a number of ground-based optical facilities.
Buzzoni +17 more
core +4 more sources
Advanced Science, EarlyView.Glutamine deprivation triggers transient DNA damage yet activates adaptive repair in hepatocellular carcinoma cells. We identify TRIB3 as a stress‐induced nuclear scaffold that associates with DDX5 and G‐quadruplex DNA atBRCA1 andRAD51AP1 promoters. TRIB3 loss increases G4 accumulation, suppresses HR gene transcription, elevates γ‐H2A.X, and sensitizes
Qiang Ji +10 more
wiley +1 more source