Results 41 to 50 of about 312,980 (227)

ICOS‐ImmunoPET Monitors T Cell Activation After Combination Immune Checkpoint Blockade in a Mouse Model of Melanoma Brain Metastasis

Advanced Science, EarlyView.
ICOS‐immunoPET noninvasively visualizes activated T cells in melanoma brain metastases following combined anti‐PD‐1/anti‐CTLA‐4 therapy. Clinical translation of this imaging approach may improve patient stratification and treatment monitoring and serve as a quantitative imaging endpoint to support immunotherapy development and clinical trials in brain ...
Renesmee C. Kuo, Rohit Verma, Sydney C. Nagy, Mausam Kalita, Samuel Aubert, Josué Ballesteros‐Álvarez, Pedro Machado Almeida, Hannes Vogel, Israt S. Alam, Michael Lim, Michelle L. James   +10 more
wiley   +1 more source

Splitting of Long-period Comet C/2018 F4 (PANSTARRS)

The Astronomical Journal, 2023
Long-period comet C/2018 F4 (PANSTARRS) was observed to show duplicity of its inner region in 2020 September, suggestive of a splitting event. We here present analyses of our observations of the comet taken from the LCO Outbursting Objects Key project ...
Man-To Hui, Michael S. P. Kelley, Denise Hung, Tim Lister, Joseph Chatelain, Edward Gomez, Sarah Greenstreet   +6 more
doaj   +1 more source

Biomonitoring of the genotoxic potential of aqueous extracts of soils and bottom ash resulting from municipal solid waste incineration, using the comet and micronucleus tests on amphibian (Xenopus laevis) larvae and bacterial assays (MutatoxR and Ames tests) [PDF]

, 2006
The management of contaminated soils and wastes is a matter of considerable human concern. The present study evaluates the genotoxic potential of aqueous extracts of two soils (leachates) and of bottom ash resulting from municipal solid waste ...
Gauthier, Laury, Devaux, Alain, Gauthier, L., Triffault, Gaëlle, Mouchet, F., Ferrier, V., Mouchet, Florence, Jourdain, M.J., Jourdain, Marie-José, Ferrier, Vincent, Triffault, G., Mailhes, Corinne   +11 more
core   +1 more source

An Optimized Freeze‐Dry Multimodal Workflow for Sequential Micro‐CT Imaging, Histology, and Molecular Profiling: A Use Case in Human Liver Fibrosis

Advanced Science, EarlyView.
Optimized freeze‐drying and eosin staining deliver artifact‐free micro‐CT images of liver tissue at near‐histological detail, then hand the same specimen back for sectioning, staining, and sequencing. Fibrotic volume distinguishes normal liver from cirrhosis, while preserved RNA reveals inflammatory gene upregulation—one biopsy, three dimensions, and a
Kristijan Skok, Laura Činč Ćurić, Jernej Vajda, Silvia Schauer, Martin Wagner, Rudolf Stauber, Carolin Lackner, Karl Kashofer, Markus Plass, Giovanny Rodriguez Blanco, Ian R. Wanless, Uroš Maver, Katrin Panzitt, Boštjan Vihar   +13 more
wiley   +1 more source

On the role of collisions with meteoroids in splitting and acceleration of heliocentric velocity of comets

Open Astronomy, 2020
The hypothesis on the role of the meteoroid impacts in the comet nuclei splitting as well as acceleration of their heliocentric velocity are considered.
Guliyev Ayyub, Guliyev Rustam
doaj   +1 more source

Comet Nuclei Composition and Evolution

Thanks to Rosetta orbiter's and Philae lander's data our knowledge of cometary nuclei composition has experienced a great advancement. The properties of 67P/CG nucleus are discussed and compared with other comets explored in the past by space missions.
Filacchione, Gianrico, Ciarniello, Mauro, Fornasier, Sonia, Raponi, Andrea   +3 more
openaire   +2 more sources

TESS-CoMET

, 2018
R script to calculate CoMET function in ...
Guillermo Ortí (69121), Ortí, Guillermo, Rafael Rivero-Vega (6001235), Davis, Aaron, Rivero-Vega, Rafael, Emanuell Duarte Ribeiro (6001232), Aaron Davis (205288), Ricardo Betancur-R (245801), Duarte Ribeiro, Emanuell, Betancur-R, Ricardo   +9 more
core   +1 more source

Macrophage RSAD2 Couples mtDNA Synthesis With a Self‐Amplifying Inflammatory Circuit to Orchestrate Tissue Repair

Advanced Science, EarlyView.
Macrophage RSAD2 dually regulates CMPK2—the rate‐limiting enzyme for mitochondrial DNA synthesis—by suppressing its ubiquitination and promoting its phosphorylation via Csnk2a2 recruitment. This amplifies mtDNA production, which simultaneously activates a cGAS‐STING‐IRF3‐RSAD2 feedforward loop and the NLRP3 inflammasome, driving a self‐sustaining ...
Haomiao Yuan, Shukui Du, Chunfei Li, Xinjie Li, Shuyang Mu, Anran Qu, Hengxu Yan, Chongchong Xu, Jinnong Yang, Jingkai Sun, Yijun Wang, Jiayang Xiao, Fuyuan Zhang, Linlin Wang, Tiegang Li, Rui Zhao, Dawei Guan   +16 more
wiley   +1 more source

Evaluation of genotoxic activity of maleic hydrazide, ethyl methane sulfonate, and N-nitroso diethylamine in Tradescantia

Salud Pública de México, 2001
Objective. To assess the genotoxic activity of N-nitroso diethylamine (NDEA), maleic hydrazide (MH), and ethyl methane sulfonate (EMS) using two systems: the comet assay on nuclei from Tradescantia, and the pink mutation test on Tradescantia staminal ...
Alvarez-Moya Carlos, Santerre-Lucas Anne, Zúñiga-González Guillermo, Torres-Bugarín Olivia, Padilla-Camberos Eduardo, Feria-Velasco Alfredo   +5 more
doaj  

comet-utilities: MS Thesis Release

, 2015
<p>This Release includes all the required material for Matias Giorgio's MS Thesis: COMET Analyzer, RabbitMQ-to-MongoDB bridge, and other modules.</p ...
Matias Giorgio
core   +1 more source