Results 51 to 60 of about 511,772 (244)

Comparison Between Different DNA and Conventional

مجله كليه طب الكندي, 2012
Background: The discriminative power of the classical WHO parameters in relation to male fertility is quite low, because they only address few aspects of sperm quality and function.
Estabraq . , A Rasool1, Omar . , F Abdul-Rasheed1, Ali F. AL-Hashimi   +2 more
doaj  

Arid1a Deficiency Drives Aristolochic Acid‐Induced Liver Tumorigenesis through Ctnnb1 Mutation and Defective Nucleotide Excision Repair

Advanced Science, EarlyView.
ARID1A is frequently mutated in both non‐malignant tissues and cancers, but its role in tumor development after exposure to genotoxic carcinogen remains unclear. It is found that aristolochic acid I accelerated liver tumorigenesis in ARID1A‐deficient context by impairing nucleotide excision repair and enhancing carcinogen bioactivation, revealing key ...
Lan Wang, Shi‐Hao Bai, Shu‐Jin Song, Xiao‐Li Zhang, Xue‐Ying Shang, Zhao‐Ning Lu, Xiao‐Fang Cui, Xin‐Le Zhu, Ze‐Guang Han   +8 more
wiley   +1 more source

Crater Observing Bioinspired Rolling Articulator (COBRA)

Advanced Intelligent Systems, EarlyView.
Crater Observing Bio‐inspired Rolling Articulator (COBRA) is a modular, snake‐inspired robot that addresses the mobility challenges of extraterrestrial exploration sites such as Shackleton Crater. Incorporating snake‐like gaits and tumbling locomotion, COBRA navigates both uneven surfaces and steep crater walls.
Adarsh Salagame, Henry Noyes, Eric Sihite, Arash Kalantari, Alireza Ramezani   +4 more
wiley   +1 more source

Solar Wind Interactions with Comet C/2021 A1 Using STEREO HI and a Data-assimilative Solar Wind Model

The Astrophysical Journal
Cometary tails display dynamic behavior attributed to interactions with solar wind structures. Consequently, comet-tail observations can serve as in situ solar wind monitors.
Sarah R. Watson, Christopher J. Scott, Mathew J. Owens, Luke A. Barnard   +3 more
doaj   +1 more source

Skeletal pathologies in extant crocodilians as a window into the paleopathology of fossil archosaurs

The Anatomical Record, EarlyView.
Abstract Crocodilians, together with birds, are the only extant relatives to many extinct archosaur groups, making them highly important for interpreting paleopathological conditions in a phylogenetic disease bracketing model. Despite this, comprehensive data on osteopathologies in crocodilians remain scarce.
Alexis Cornille, Kyla Beguesse, Ewan Wolff, Clemens Zinner, Patrick Asbach, François Clarac, Florian Witzmann   +6 more
wiley   +1 more source

In vivo comet assay in rabbit corneal epithelial cells following ocular instillation with genotoxic compounds

Genes and Environment, 2021
Background The in vivo comet assay is used to evaluate the genotoxic potential of compounds by detecting DNA strand breaks in cells isolated from animal tissue.
Haruna Tahara, Yoshinori Yamagiwa, Yu Haranosono, Masaaki Kurata   +3 more
doaj   +1 more source

Transferability and Reproducibility of the HepaRG CometChip Assay

Environmental and Molecular Mutagenesis, EarlyView.
ABSTRACT This interlaboratory evaluation of HepaRG CometChip was conducted to assess transferability and reproducibility of this new approach methodology (NAM) across four laboratories. Concentrations inducing up to ~70% relative cytotoxicity were determined by the organizing laboratory, and frozen chemical formulation blocks were sent to each ...
Leslie Recio, Carol Swartz, Lincoln Martin, Emily Rottinger, Stefan Pfuhler, Erica Pinkus, Daniel J. Roberts, Leon F. Stankowski, Simran Kaushal, Norah A. Owiti, Bevin P. Engelward   +10 more
wiley   +1 more source

Detection of Hypoxia in Human Brain Tumor Xenografts Using a Modified Comet Assay

Neoplasia: An International Journal for Oncology Research, 2003
We used the standard comet assay successfully to generate in vitro dose-response curves under oxic and hypoxic conditions. We then made mixtures of cells that had been irradiated with 3 and 9 Gy of X-rays to simulate two subpopulations in a tumor, but ...
Jingli Wang, Jack Klem, Jan B. Wyrick, Tomoko Ozawa, Erin Cunningham, Jay Golinveaux, Max J. Allen, Kathleen R. Lamborn, Dennis F. Deen   +8 more
doaj   +1 more source

Acute Toxicity and Genotoxicity of cMoL, a Lectin From Moringa oleifera Seeds With Antifungal Activity Against Cryptococcus Strains

Journal of Applied Toxicology, EarlyView.
ABSTRACT Coagulant Moringa oleifera lectin (cMoL) is one of the compounds involved in the application of M. oleifera seeds for traditional water treatment methods. The present study highlights the new biotechnological potential of cMoL lectin as an antifungal agent against Cryptococcus neoformans B3501 and H99 and Cryptococcus gattii R265 strains ...
Matheus Cavalcanti de Barros, Sávia Soraia Santana da Silva, Eduarda Pinto Gagliano, Alícia Natalie Silva dos Santos, Leydianne Leite de Siqueira Patriota, Gustavo Ramos Salles Ferreira, Pollyanna Michelle da Silva, Simone da Paz Leôncio Alves, Julliano Matheus de Lima Maux, Jacinto da Costa Silva Neto, Fernanda Rafaelly Nascimento de Santana, Fabiana Aparecida Cavalcante Silva, Marilene Henning Vainstein, Luana Cassandra Breitenbach Barroso Coelho, Thâmarah de Albuquerque Lima, Thiago Henrique Napoleão, Patrícia Maria Guedes Paiva   +16 more
wiley   +1 more source

Pulmonary scan in evaluating alveolar-interstitial syndrome in ER

Emergency Care Journal, 2006
Diffuse comet-tail artifacts at lung ultrasound are due to thickened interlobular septa and extravascular lung water. This condition is typical of the alveolar-interstitial syndrome due to pulmonary edema, diffuse parenchymal lung disease or ARDS. Aim of
Giovanni Volpicelli, Alessandro Mussa, Giovanna Casoli, Giorgio Garofalo, Luciano Cardinale, Fabio Perotto, Mauro Frascisco   +6 more
doaj   +1 more source