Results 21 to 30 of about 4,435 (243)

Results of the COVID-19 mental health international for the general population (COMET-G) study

open access: yesEuropean Neuropsychopharmacology, 2022
INTRODUCTION: There are few published empirical data on the effects of COVID-19 on mental health, and until now, there is no large international study. MATERIAL AND METHODS: During the COVID-19 pandemic, an online questionnaire gathered data from 55,589 participants from 40 countries (64.85% females aged 35.80 ± 13.61; 34.05% males aged 34.90±13.29 and
Konstantinos N Fountoulakis   +156 more
openaire   +6 more sources

Building a Weakly Outgassing Comet from a Generalized Ohm’s Law

open access: yesPhysical Review Letters, 2019
When a weakly outgassing comet is sufficiently close to the Sun, the formation of an ionized coma results in solar wind mass loading and magnetic field draping around its nucleus. Using a 3D fully kinetic approach, we distill the components of a generalized Ohm's law and the effective electron equation of state directly from the self-consistently ...
Deca, J.   +7 more
openaire   +5 more sources

Towards a New Generation of Widgets for Supporting Software Plasticity: The ”Comet” [PDF]

open access: yes, 2005
This paper addresses software adaptation to context of use. It goes one step further than our early work on plasticity [5]. Here, we propose a revision of the notion of software plasticity that we apply at the widget level in terms of comets. Plasticity is defined as the ability of an interactive system to withstand variations of context of use while ...
Gaëlle Calvary   +4 more
openaire   +1 more source

Performance Assessment of the COMET Cloud Fractional Cover Climatology across Meteosat Generations [PDF]

open access: yesRemote Sensing, 2018
The CM SAF Cloud Fractional Cover dataset from Meteosat First and Second Generation (COMET, https://doi.org/10.5676/EUM_SAF_CM/CFC_METEOSAT/V001) covering 1991–2015 has been recently released by the EUMETSAT Satellite Application Facility for Climate Monitoring (CM SAF).
Jedrzej S. Bojanowski   +4 more
openaire   +2 more sources

Spiro‐Phenothiazine Hole‐Transporting Materials: Unlocking Stability and Scalability in Perovskite Solar Cells

open access: yesAdvanced Materials, EarlyView.
Fluorene‐functionalized spiro‐phenothiazine (PTZ‐Fl) exhibits strong Li+ affinity and thermal stability, enabling a PCE of 25.75% in small‐area cells and 22.07% in 25 cm2 modules. Under ISOS‐L3 conditions, PTZ‐Flbased devices retain over 80% efficiency after 1000 hours, demonstrating superior stability and scalability compared to spiro‐OMeTAD for next ...
Javier Urieta‐Mora   +17 more
wiley   +1 more source

Automated Dynamic Flow Experimentation for Rapid Kinetic Fitting of Transition Metal Catalysis

open access: yesAngewandte Chemie, EarlyView.
We have developed an automated dynamic flow experimentation platform to automatically fit and identify the most accurate kinetic model from a generated set of candidates. Three transition metal‐catalyzed transformations were performed using this workflow.
Florian L. Wagner   +3 more
wiley   +2 more sources

Photocatalytic Water Splitting on the Lunar Surface: Prospects for In Situ Resource Utilization

open access: yesAdvanced Materials Interfaces, EarlyView.
Water has been found in craters on the moon nearby locations which are illuminated >80% of the time. Photocatalysis uses energy from sunlight to drive chemical reactions such as water splitting to produce oxygen and hydrogen. It is a scalable technology that requires lighter equipment and utilizes resources available on the moon. ABSTRACT The discovery
Ranjani Kalyan   +6 more
wiley   +1 more source

DMAP1 Deficiency Suppresses Lung Cancer Progression by Destabilizing Replication Fork and Activating IFN Signaling‐Mediated Anti‐tumor Immunity

open access: yesAdvanced Science, EarlyView.
Lung cancer remains the leading cause of cancer‐related death. We investigated the role of the epigenetic regulator DMAP1 in NSCLC and found that its loss induces replication stress and DNA damage. This in turn activates type I IFN signaling via the cGAS–STING pathway and transcriptional ISG de‐repression, enhancing anti‐tumor immune responses ...
Kan Huang   +10 more
wiley   +1 more source

SMAD4 Palmitoylation Drives a Metabolic‐Transcriptional Circuit to Promote Tumorigenesis and Confers Radiosensitivity in Pancreatic Cancer

open access: yesAdvanced Science, EarlyView.
This study identifies palmitoylation as a novel regulatory modification of SMAD4, mediated by ZDHHC22/APT2. It activates fatty acid synthesis, creating a self‐reinforcing SMAD4–FASN–palmitate feedback loop that drives pancreatic cancer growth and enhances radiotherapy sensitivity.
Yang Wang   +16 more
wiley   +1 more source

Inhibition of SIRT7 Overcomes Radioresistance in Pancreatic Neuroendocrine Tumors by Reactivating MEN1 Expression

open access: yesAdvanced Science, EarlyView.
Pancreatic neuroendocrine tumors frequently silence MEN1 through epigenetic mechanisms. Here, SIRT7 recruits DNMT1 to the MEN1 promoter, drives hypermethylation, and enhances DNA repair. Inhibiting SIRT7 restores MEN1, reduces MRN complex abundance, impairs double‐strand break repair, and sensitizes PanNET models to radiation, supporting SIRT7 as a ...
Jianyun Jiang   +11 more
wiley   +1 more source

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