Results 51 to 60 of about 24,316 (300)
ANXA2+ sEVs promote cisplatin resistance in ATC by stabilizing the SRC/LDHA interaction, increasing LDHA phosphorylation and activity, and lactate production. Elevated lactate levels promote KAT5‐mediated lactylation of XRCC5 at lysine 265, enhancing its binding to XRCC6.
Shanshan Su +4 more
wiley +1 more source
This poster shows images of comets Hale-Bopp and Shoemaker-Levy 9. The accompanying text describes possible source regions for comets in our solar system, the behavior of comets as they approach the Sun, their possible role in the evolution of Earth, and
core +2 more sources
Are the main belt comets, comets? [PDF]
AbstractWe present the visible spectrum of asteroid-comet transition object 133P/Elst-Pizarro (7968), the first member of the new population of objects called Main Belt Comets (Hsieh & Jewitt 2006). The spectrum was obtained with the 4.2m William Herschel Telescope at the “Roque de los Muchachos” observatory.
Javier Licandro, Humberto Campins
openaire +1 more source
Infrared observations of faint comets [PDF]
Infrared observations of the periodic comets Encke, Stephan-Oterma and Chernykh indicate that the dusty component in this class of comets is not radically different from the dusty component found in nonperiodic comets.
Rieke, G. +3 more
core
USP10 binds to and stabilizes PFKFB4, enhancing glycolytic ATP production, which activates the urea cycle and elevates fumarate. This inhibits histone demethylase KDM1A, leading to increased H3K4me1 enrichment at the Rad51 promoter and direct activation of Rad51 transcription, which confers lung cancer radioresistance. The PFKFB4 inhibitor 5MPN targets
Yunshang Chen +7 more
wiley +1 more source
How Meteor Showers Can Guide the Search for Long-period Comets
With orbital periods longer than 200 yr, most long-period comets (LPCs) remain undiscovered until they are in-bound toward perihelion. The comets that pass close to Earth’s orbit are potentially hazardous objects.
Samantha Hemmelgarn +3 more
doaj +1 more source
To effectively reverse TMZ resistance, this work proposes a cuproptosis‐mediated positive feedback loop that integrates mitochondrial dysfunction, ATP depletion, AMPK‐p53 signaling, and glycolytic inhibition, ultimately amplifying cell death. This cuproptosis‐mediated feedback loop simultaneously disrupts multiple resistance pathways in GBM, including ...
Wenjie Feng +9 more
wiley +1 more source
Databases of major planets coordinates are created on the basis of the numerical theory of movement of planets DE405. Numerical integration of the motion equations of small bodies of Solar system is realized using the received databanks. Extra efficiency
Vladimir P Radchenko, Dmitriy A Zausaev
doaj
Abstract The fact that comets are rich in volatile material shows that they were formed and kept for a long time in the outer, low-temperature regions of the solar system. In this paper we analyse the structure in the outer edge of the solar nebula and show that no formation zone of comets can exist there. Our view is that the comets evolved from the
null Hu Zhong-wei, null Yang Ke-zhong
openaire +1 more source

