Results 61 to 70 of about 188,912 (301)

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

open access: yesFEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point   +7 more
wiley   +1 more source

Mission Command when waging cyber operations

open access: yes, 2019
The conditions for military operations have changed due to many things and the cyber-related challenges associated with these conditions require more attention.
Norlander, Arne   +3 more
core  

Exon 7 splicing of ERα predicts poor prognosis and increases phenotypic heterogeneity in luminal a subtype breast cancer

open access: yesFEBS Open Bio, EarlyView.
ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui   +10 more
wiley   +1 more source

Exploring Mission Command in a Concept for Future Command and Control

open access: yes, 2018
Future Command and Control (C2) need to be both agile and resilient to cope with unpredictable operational environments and to make use of the technological advances. The Swedish Armed Forces develops a concept for future C2 of military operations.
Barius, Per   +3 more
core  

A decision-making framework using MCTS as a hierarchical task network and deep learning connector

open access: yesScience Progress
Currently, purely deep learning-based agents struggle to make optimal decisions within a short timeframe in problems with a vast decision-making space. Human planning knowledge is required to assist agents in making better decisions.
Tianhao Shao   +3 more
doaj   +1 more source

Decreased cold‐sensing function of the transient receptor potential channel TRPM8 from tailed amphibians

open access: yesFEBS Open Bio, EarlyView.
Despite frogs avoiding low temperatures, examination of four salamander species revealed that none avoided cold and all possessed cold tolerance. Functional analysis of TRPM8, a cold sensor, showed that all salamander TRPM8s had lost their cold sensitivity.
Tadahiro Sawao   +3 more
wiley   +1 more source

Current status of information management construction and future development directions for disease prevention and control institutions in China

open access: yesZhongguo gonggong weisheng
Information management departments within Chinese Center for Disease Control and Prevention (CDC) agencies played a crucial role in the control of the novel coronavirus disease (COVID-19) pandemic, and their importance has become increasingly prominent ...
Han WEI   +5 more
doaj   +1 more source

Air Mission Commander. Command and Control [PDF]

open access: yesLand Forces Academy Review, 2020
Abstract In the fight management, the military commander, who is assimilated to a leader has, most of the time, the most important role. Today, in addition to the traditional missions to defend the sovereignty, independence and territorial integrity of the state, the military forces also carry out missions according to the obligations
openaire   +1 more source

YIPFα1A expression is regulated by multilayered molecular mechanisms

open access: yesFEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji   +2 more
wiley   +1 more source

Modelling command and control : the challenge of integrating structure and behaviour

open access: yes, 2018
This paper presents an introduction to why it is difficult, and still desirable, to integrate the perspectives of structure and behaviour when modelling command and control (C2).
Spak, Ulrik, Carlerby, Mats
core  

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