Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Minimal-Intrusion Traffic Monitoring And Analysis In Mission-Critical Communication Networks [PDF]
A good knowledge of expected and actual traffic patterns is an essential tool for network planning, design and operation in deployed, mission-critical applications.
Alberto Domingo Ajenjo +1 more
doaj
Nowhere to Hide Methodology: Application of Clustering Fault Diagnosis in the Nuclear Power Industry
When a system crashes, fast and accurate log-based fault diagnosis can remarkably reduce the recovery time of the system and avoid further economic losses. Especially for the nuclear power industry, recovery time will lead not only to economic losses but
Cheng Zong +4 more
doaj +1 more source
Spatial‐temporal slowfast graph convolutional network for skeleton‐based action recognition
In skeleton‐based action recognition, the graph convolutional network (GCN) has achieved great success. Modelling skeleton data in a suitable spatial‐temporal way and designing the adjacency matrix are crucial aspects for GCN‐based methods to capture ...
Zheng Fang +4 more
doaj +1 more source
Epigenetic reprogramming of lineage switching in cancer
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source
Mission Command when waging cyber operations
The conditions for military operations have changed due to many things and the cyber-related challenges associated with these conditions require more attention.
Norlander, Arne +3 more
core +1 more source
Application of the modular Command and Control Evaluation Structure to a Strategic Defense Initiative command and control system [PDF]
This thesis will focus on relating a generic evaluation structure, the Modular Command and Control Evaluation Structure (MCES) to the battle management (B\Ml) and command, control and communication (C3) issues of the Strategic Defense Initiative (SDI ...
Kramer, Gail K.
core +2 more sources
A noise-robust voice conversion method with controllable background sounds
Background noises are usually treated as redundant or even harmful to voice conversion. Therefore, when converting noisy speech, a pretrained module of speech separation is usually deployed to estimate clean speech prior to the conversion.
Lele Chen +4 more
doaj +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Exploring Mission Command in a Concept for Future Command and Control
Future Command and Control (C2) need to be both agile and resilient to cope with unpredictable operational environments and to make use of the technological advances. The Swedish Armed Forces develops a concept for future C2 of military operations.
Barius, Per +3 more
core +1 more source

