Results 61 to 70 of about 699,167 (308)

Suppression of lung adenocarcinoma migration through organelle alkalization by human lactoferrin – albumin fusion

FEBS Open Bio, EarlyView.
This paper reveals how human lactoferrin–albumin fusion (hLF‐HSA) potently suppresses lung adenocarcinoma cell migration. hLF‐HSA upregulates NHE7, leading to Golgi alkalization, disruption of the Golgi secretome, downregulation of MMP1, and reversal of EMT. These findings suggest a novel Golgi‐targeting strategy to suppress cancer cell migration.
Hana Nopia, Masahiro Kimura, Daisuke Kurimoto, Atsushi Sato   +3 more
wiley   +1 more source

Les révoltes dans les ports maritimes normands au xviiie siècle

Cahiers d’histoire, 2005
L’étude des révoltes dans les ports maritimes normands au xviiie siècle présente pour intérêt de montrer la diversité des comportements dans les sociétés urbaines d’une même province.
Eric Saunier
doaj   +1 more source

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

FEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer, Angelique Kragl, Katrin Ziems, Juliane Glaubitz, Sophie Grammbauer, Susanne Hildebrandt, Mladen V. Tzvetkov, Gabriele Jedlitschky   +7 more
wiley   +1 more source

La Bourse de commerce promenade architecturale [PDF]

, 2021
La Collection Pinault fait événement en ouvrant, dans la Bourse de Commerce de Paris, un musée d'art contemporain. Pour transformer ce lieu historique situé au cœur de la capitale, François Pinault s'est adressé, comme il l'avait déjà fait à Venise, à ...
Picon, Guillaume 1974-, Bourse de commerce - Pinault collection   +1 more
core  

The impact of electronic commerce adoption on the performance of microenterprises: Do technological context, organizational context, and external environment matter? [PDF]

Problems and Perspectives in Management
Electronic commerce is gaining importance as a hub for product sourcing, helping businesses earn a competitive edge, and connecting with consumers. Despite its enormous benefits, very few microenterprises in Indonesia adopted electronic commerce.
Suyanto Suyanto, Arvin Winatha, Olivia Tanaya   +2 more
doaj   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

FEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young, Omar Arias‐Gaguancela, Fiona Gibson, Morgan Grainger, Jodie Score, Amit Nathubhai, Mauricio Cafiero, Lee Richard Machado   +7 more
wiley   +1 more source

Commercialization of Medicinal Plants in Java Island, Indonesia

Jurnal Manajemen Hutan Tropika, 2016
The benefit and transaction cost flow which people earn economically and socially from wild medicinal plant harvesting are addressed in this study. The objectives of this study are three aspects: defining how many users are involved in utilization of ...
Ignatius Adi Nugroho, Dodik Ridho Nurrochmat, Hardjanto   +2 more
doaj   +1 more source

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

FEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee, Giulia Zanetti, Bram van den Broek, Kees Jalink   +3 more
wiley   +1 more source

Determining the value of connoisseurship – an art of lasting topicality [PDF]

Journal of Art Historiography, 2017
Copy.Right – Adam von Bartsch – Kunst, Kommerz, Kennerschaft published by Stephan Brakensiek, Anette Michels, and Anne-Katrin Sors promises to open up fresh perspectives on the art, commerce and connoisseurship in 1800 – and appeared to coincide with the
Peter-David Friedrich
doaj  

Acute caffeine treatment protects the developing retina from ischemia‐induced cell death

FEBS Open Bio, EarlyView.
Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento, Danniel Pereira‐Figueiredo, Gabriella Grossi de Lima Dias, Gabriel Ferreira dos Santos, Mariana Rodrigues Pereira, Rafael Brito, Karin C Calaza   +6 more
wiley   +1 more source