Results 41 to 50 of about 1,974,871 (309)

Feasibility of a ctDNA multigenic panel for non‐small‐cell lung cancer early detection and disease surveillance

Molecular Oncology, EarlyView.
Plasma‐based detection of actionable mutations is a promising approach in lung cancer management. Analysis of ctDNA with a multigene NGS panel identified TP53, KRAS, and EGFR as the most frequently altered, with TP53 and KRAS in treatment‐naïve patients and TP53 and EGFR in previously treated patients.
Giovanna Maria Stanfoca Casagrande, Marcela de Oliveira Silva, Mariana Bisarro dos Reis, Rodrigo de Oliveira Cavagna, Luciane Sussuchi, Icaro Alves Pinto, Natalia Zampieri Pontes, Rodrigo Sampaio Chiarantano, Flavio Augusto Ferreira da Silva, Pedro de Marchi, Letícia Ferro Leal, Rui M. Reis   +11 more
wiley   +1 more source

Attribute Perception Mapping Services Domestic Airlines Using Correspondence Analysis [PDF]

International Research Journal of Business Studies, 2015
Positioning analysis provides a better understanding of the position based on the perception of passenger flights to service these attributes attached to each airline.
Reni Heviandri Riandarini, Ujang Sumarwan, Kirbrandoko, Lilik Noor   +3 more
doaj  

Glycosylated LGALS3BP is highly secreted by bladder cancer cells and represents a novel urinary disease biomarker

Molecular Oncology, EarlyView.
Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece, Giulio Lovato, Ilaria Cela, Arianna Mercatelli, Benedetta Ferro, Jussi Nikkola, Sara Pagotto, Tommaso Grottola, Vincenzo De Laurenzi, Rossella Cicchetti, Antonio Marchetti, Luigi Schips, Rossano Lattanzio, Stefano Iacobelli, Emily Capone, Peter Black, Mads Daugaard, Michele Marchioni, Gianluca Sala   +18 more
wiley   +1 more source

Learning lessons? The registration of lobbyists at the Scottish parliament: a reply to Coldwell [PDF]

, 2006
The Scottish Parliament was founded on principles of openness and accessibility and signalled the potential for a new style of politics post devolution.
Dinan, William
core   +1 more source

Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA

Molecular Oncology, EarlyView.
Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson, Anders Lade Nielsen, Boe Sandahl Sorensen   +2 more
wiley   +1 more source

Impact of COVID-19 on people with non-functioning spleens in Australia

Journal of Infection and Public Health
Background: COVID-19 has had enormous impact on health and social systems, with stringent public health measures enacted across Australia. The virus itself disproportionately affects immunocompromised individuals including people without functioning ...
Maeve Barlow, Penelope Jones, Mihiri Weerasuria, Jessica O’Bryan, Denis Spelman, Ian Woolley   +5 more
doaj   +1 more source

المراسلات السومرية ودورها في توثيق الحياة السياسية والاجتماعية في بلاد الرافدين: دراسة تحليلية في ضوء النصوص المسمارية [PDF]

Maǧallaẗ Kulliyyaẗ Al-ādāb Ǧāmiʿaẗ Būrsaʿīd
استنادًا إلى أن التاريخ لا يمكن أن يُكتب دون وثيقة تبرز الوثائق كمصدر رئيسي لتوثيق الأحداث التاريخية، وتعد المراسلات إحدى أرقى الإبداعات الإنسانية التي استخدمها الإنسان القديم للتواصل وتبادل المعرفة.
حسام محمد عبدالفتاح هلال حجازي
doaj   +1 more source

An investigation of thresholds in air pollution-mortality effects [PDF]

, 2004
In this paper we introduce and implement new techniques to investigate threshold effects in air pollution-mortality relationships. Our key interest is in measuring the dose-response relationship above and below a given threshold level where we allow for ...
Clyde, Daniels, Delfino, Dockery, Dominici, Draper, Fairly, Fernandez, Fernandez, Gary Koop, Hodges, Hoeting, Hurley, Koop, Koop, Lim, Lise Tole, Madigan, Meng, Ordieres, Ostro, Pope, Raftery, Schwartz, Schwartz, Schwartz, Schwartz, Schwartz, Schwartz, Schwartz, Schwartz, Schwartz, Schwartz, Schwartz, Schwartz, Smith, Xu   +36 more
core   +1 more source

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

Molecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz, Anna L. Bartkowiak, Michael Rose, Nora Kolks, Patrick Petzsch, Vandana Solanki, Anne Stoffel, Bianca Faßbender, Leandra Lepping, Julka Volkamer, Karl Köhrer, Marc Seifert, Tokameh Mahmoudi, Tahlita C. M. Zuiverloon, Günter Niegisch, Michèle J. Hoffmann   +15 more
wiley   +1 more source

Chinese entrepreneurship in context: specialization, localization and their impact on Italian industrial districts [PDF]

, 2011
Chinese migration flows represent a relatively new phenomenon in Italy. Its entrepreneurial nature is reflected in massive flows Chinese businessman employed both in manufacturing and commercial activities, with a dense concentration in correspondence of
Lombardi, Silvia, Sforzi, Fabio, Verrecchia, Flavio   +2 more
core