Results 51 to 60 of about 1,974,871 (309)
Molecular Oncology, EarlyView.HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
Performance Measurement Systems, Competitive Priorities, and Advanced Manufacturing Technologies: Some Evidence from the Aeronautical Sector [PDF]
, 2005 Purpose – When acquiring advanced manufacturing technologies (AMT), the greatest caution should be taken regarding the performance measurement system to be used: the decision regarding new investments should not be conditioned by the excessive use of ...
Dominguez Machuca, José A. +2 more
core +3 more sources
Molecular Oncology, EarlyView.Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad +12 more
wiley +1 more source
Secretarial Work as a Profession [PDF]
, 1923 Brochure promoting Bryant\u27s 1923 secretarial program and its ...
core +1 more source
Removal of electrostatic artifacts in magnetic force microscopy by controlled magnetization of the tip: application to superparamagnetic nanoparticles [PDF]
, 2016 Magnetic force microscopy (MFM) has been demonstrated as valuable technique for the characterization of magnetic nanomaterials. To be analyzed by MFM techniques, nanomaterials are generally deposited on flat substrates, resulting in an additional ...
ANGELONI, LIVIA +4 more
core +1 more source
Molecular Oncology, EarlyView.We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto +8 more
wiley +1 more source
Dificultades del urbanismo comercial: el Plan General de Equipamiento Comercial de Castilla y León [PDF]
Ciudades, 2007 The retail network in Castilla y León has a clear correspondence with the regional urban system, with its weakness and its singularities. The development of new big retail structures and malls, clearly underdeveloped comparing with other Spanish Regions,
Juan Luis de las Rivas Sanz
doaj
Studia Historica: Historia Moderna, 2020 This article addresses the issue of shipping trade between the American ports of the Philadelphia district and those of New England with Spain, during the turbulent years of the late eighteenth century. First, the US consular network in Spain is analyzed,
Guadalupe CARRASCO GONZÁLEZ
doaj +1 more source
Guide to the Erath Winery Collection [PDF]
, 2016 The collection was donated by Dick Erath, the founder of Erath Winery in Dundee, Oregon. The collection contains financial information about the winery, publicity found in newspapers and magazines, details of the winemaking process, multiple drafts of ...
Linfield College Archives
core +1 more source