Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma
Molecular Oncology, EarlyView.Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra +6 more
wiley +1 more source
Aldus Manutius, the Gonzagas and a Lucky Frenchman. Some Examples from Aldus's Letters
TECAAmong the letters written and received by Aldus Manutius, the ones held in the Archivio di Stato in Mantua are very interesting and rich in rare Aldus’s autographs.
Stefano Cassini
doaj +1 more source
Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics
FEBS Open Bio, EarlyView.Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini +2 more
wiley +1 more source
Chinese entrepreneurship in context: specialization, localization and their impact on Italian industrial districts [PDF]
Chinese migration flows represent a relatively new phenomenon in Italy. Its entrepreneurial nature is reflected in massive flows Chinese businessman employed both in manufacturing and commercial activities, with a dense concentration in correspondence of
Fabio Sforzi +2 more
core
Valuing knowledge transfer : a new approach to assessing the broader impact of higher education institutions [PDF]
, 2009 There is considerable policy interest in exploring the overall value of higher education to society and in how higher education can support wider economic growth and development through 'knowledge transfer' from higher education institutions.
Kelly, Ursula +3 more
core
UV Degradation of the Optical Properties of Acrylic for Neutrino and Dark Matter Experiments [PDF]
, 2009 UV-transmitting (UVT) acrylic is a commonly used light-propagating material in neutrino and dark matter detectors as it has low intrinsic radioactivity and exhibits low absorption in the detectors' light producing regions, from 350 nm to 500 nm ...
+16 more
core +2 more sources
Homologous expression and purification of human HAX‐1 for structural studies
FEBS Open Bio, EarlyView.This research protocol provides detailed instructions for cloning, expressing, and purifying large quantities of the intrinsically disordered human HAX‐1 protein, N‐terminally fused to a cleavable superfolder GFP, from mammalian cells. HAX‐1 is predicted to undergo posttranslational modifications and to interact with membranes, various cellular ...
Mariana Grieben
wiley +1 more source
Impact Investing and Inclusive Business Development in Africa: A research agenda [PDF]
, 2015 Impact investing aims to create sustainable social and environmental impacts for investee enterprises and communities as well as adequate financial returns.
Korda, Alex +2 more
core
Using ACL2 to Verify Loop Pipelining in Behavioral Synthesis [PDF]
, 2014 Behavioral synthesis involves compiling an Electronic System-Level (ESL) design into its Register-Transfer Level (RTL) implementation. Loop pipelining is one of the most critical and complex transformations employed in behavioral synthesis.
Hao, Kecheng +3 more
core +4 more sources
FEBS Open Bio, EarlyView.Light activation of the photoswitchable cannabinoid ligand azo‐HU308 triggers Ca2+ influx in pancreatic β‐cells through TRPC channels, independent of CB2 cannabinoid receptors. This reveals a non‐GPCR pathway for cannabinoid modulation of β‐cell Ca2+ dynamics and establishes azo‐HU308 as an optical tool to study cannabinoid signaling through TRP ...
Alexander E. G. Viray, James A. Frank
wiley +1 more source