Dapagliflozin prevents methylglyoxal‐induced retinal cell death in ARPE‐19 cells
Diabetic macular oedema is a diabetes complication of the eye, which may lead to permanent blindness. ARPE‐19 are human retinal cells used to study retinal diseases and potential therapeutics. Methylglyoxal is a compound increased in uncontrolled diabetes due to elevated blood glucose.
Naina Trivedi +7 more
wiley +1 more source
Social Determinants of Health: Underreported Heterogeneity in Systematic Reviews of Caregiver Interventions. [PDF]
BACKGROUND AND OBJECTIVES:Although most people have some experience as caregivers, the nature and context of care are highly variable. Caregiving, socioeconomic factors, and health are all interrelated.
Bell, Janice F. +6 more
core +1 more source
Animal welfare in poultry production systems: impact of EU standards on world trade [PDF]
Animal welfare receives more legislative attention in the European Union (EU) than in many other regions of the world. Animal welfare standards for poultry are generally taken to be higher in the EU than in producing countries exporting to the EU ...
Achterbosch, T.J., Horne, P.L.M., van
core +2 more sources
Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli +8 more
wiley +1 more source
Small-Scale Food Animal Production and Antimicrobial Resistance: Mountain, Molehill, or Something in-between? [PDF]
SummarySmall-scale food animal production is widely practiced around the globe, yet it is often overlooked in terms of the environmental health risks.
Eisenberg, Joseph NS +4 more
core +1 more source
Development of human monoclonal antibodies against TARM1 by yeast display
Human monoclonal antibodies against TARM1 are generated by yeast display‐guided selection. These antibodies bind to soluble and cell‐surface forms of TARM1. Also, these antibodies exhibit agonistic activity in the NFAT‐GFP reporter assay, indicating that TARM1 signaling can be functionally modulated by antibodies and suggesting TARM1 as a potential ...
Rikio Yabe +5 more
wiley +1 more source
Background Rates of obesity are rising globally, with socioeconomic inequalities driving this disproportionately in lower income communities. The COVID-19 pandemic and ongoing cost-of-living crisis have further exacerbated unhealthy eating patterns ...
Aleks Saunders +3 more
doaj +1 more source
Economic and commercial determinants of health, as wellas health- related determinants of economy, are graduallybeing understood by researchers and public healthspecialists.
Sanjay Kalra +3 more
doaj +1 more source
Evaluation of TypeSeq, a Novel High-Throughput, Low-Cost, Next-Generation Sequencing-Based Assay for Detection of 51 Human Papillomavirus Genotypes. [PDF]
BackgroundHuman papillomaviruses (HPV) cause over 500 000 cervical cancers each year, most of which occur in low-resource settings. Human papillomavirus genotyping is important to study natural history and vaccine efficacy. We evaluated TypeSeq, a novel,
Boland, Joseph +20 more
core +1 more source
Prevalence, determinants and impact of unawareness about the health consequences of tobacco use among 17,929 school personnel in 29 African countries. [PDF]
Objectives: To assess prevalence, determinants and impact of unawareness about the health consequences of tobacco use among school personnel in Africa. Design: Cross-sectional surveys. Setting: Twenty-nine African countries.
Agaku, IT, Filippidis, FT
core +2 more sources

