Results 121 to 130 of about 481,541 (291)
FEBS Open Bio, EarlyView.The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer +7 more
wiley +1 more source
Institutional investment in addictive industries: an important commercial determinant of health
Frontiers in Public HealthBackgroundThe production of addictive commodities is subject to a range of commercial determinants. There has nevertheless been a gap in understanding how investments into addictive commodities may function as commercial determinants.
Sébastien Berret +3 more
doaj +1 more source
FEBS Open Bio, EarlyView.Drugs previously repurposed to target blood cancers reduced neuroblastoma and glioblastoma cell growth and viability. However, their levels of anticancer activity were different and their clinical application may be problematic due to side effects at effective doses.
Abhishek Kharawatkar +4 more
wiley +1 more source
Determinants of Credit Risk in Indian State-owned Banks: An Empirical Investigation [PDF]
The determinants of credit risk of banks in emerging economies have received limited attention in the literature. Using advanced panel data techniques, the paper seeks to examine the factors affecting problem loans of Indian state-owned banks for the ...
Das, Abhiman, Ghosh, Saibal
core +1 more source
On the Impact of Financial Inclusion on Financial Stability and Inequality: The Role of Macroprudential Policies [PDF]
, 2019 Financial Inclusion - access to financial products by households and firms - is one of the main albeit challenging priorities, both for Advanced Economies (AEs) as well as Emerging Markets (EMs), even more so for the latter.
El Said, A., Emara, N., Pearlman, J.
core +1 more source
Commercial determinants of health and sport sponsorship [PDF]
, 2019 Tobacco, alcohol and foods that are high in fat, salt and sugar generate much of the global burden of noncommunicable diseases.\ud We therefore need a better understanding of how these products are promoted. The promotion of tobacco products through sporting events\ud has largely disappeared over the last two decades, but advertising and sponsorship ...
Ireland, Robin +6 more
openaire
Discovery and Targeted Proteomic Studies Reveal Striatal Markers Validated for Huntington's Disease
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Clinical trials for Huntington's disease (HD) enrolling persons before clinical motor diagnosis (CMD) lack validated biomarkers. This study aimed to conduct an unbiased discovery analysis and a targeted examination of proteomic biomarkers scrutinized by clinical validation. Methods Cerebrospinal fluid was obtained from PREDICT‐HD and
Daniel Chelsky +8 more
wiley +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective The Gold Coast criteria permit diagnosis of amyotrophic lateral sclerosis (ALS) even without upper motor neuron (UMN) signs. However, whether ALS patients with UMN signs (ALSwUMN) and those without (ALSwoUMN) share similar characteristics and prognoses remains unclear.
Hee‐Jae Jung +7 more
wiley +1 more source
Public health education post-COVID-19: a proposal for critical revisions
BMJ Global Health, 2021 Adnan A Hyder +2 more
doaj +1 more source