Results 51 to 60 of about 157,516 (316)

One size does not fit all: An in vitro evaluation of the effects of bezafibrate and medroxyprogesterone acetate on human SH‐SY5Y and U‐87 MG cancer cells

FEBS Open Bio, EarlyView.
Drugs previously repurposed to target blood cancers reduced neuroblastoma and glioblastoma cell growth and viability. However, their levels of anticancer activity were different and their clinical application may be problematic due to side effects at effective doses.
Abhishek Kharawatkar, Francesco Michelangeli, Farhat Latif Khanim, Christopher Martin Bunce, William Eustace Basil Johnson   +4 more
wiley   +1 more source

A study on textile microfiber contamination in the gastrointestinal tracts of Merluccius merluccius samples from the Tyrrhenian Sea

Italian Journal of Food Safety
The increased demand and consumption of synthetic textiles have contributed to microplastic pollution in the form of microfibers. These particles are widely spread in the aquatic environment, leading to the exposure of marine biota, including edible ...
Serena Santonicola, Michela Volgare, Marica Erminia Schiano, Mariacristina Cocca, Giampaolo Colavita   +4 more
doaj   +1 more source

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

FEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin, Naghme Radmannia, David N. Huynh, Liliane Ménard, Caroline Daneault, Maïté Veilleux, Ahsanullah Ahsanullah, André C. Carpentier, William D. Lubell, Matthieu Ruiz, Huy Ong, Sylvie Marleau, Simon‐Pierre Gravel   +12 more
wiley   +1 more source

Clinical Spectrum and Outcomes of SOX1 Antibody‐Associated Paraneoplastic Neurological Syndromes: A Chinese Cohort Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background SOX1 antibody‐positive paraneoplastic neurological syndromes (PNS) exhibit significant population‐specific clinical heterogeneity. While Western cohorts predominantly manifest Lambert‐Eaton myasthenic syndrome (65%–80%), comprehensive clinical characterization and treatment response data in Asian populations remain critically ...
Jin‐Long Ye, Zu‐Ying Kuang, Bo Li, Meng‐Qiu Pan, Li‐Hua Zhou, Yang‐Yang Dai, Si‐Fen Xie, Xian‐Guang Lin, Ye‐Peng Hu, Li‐Hong Jiang, Zhan‐Hang Wang, Wei‐Jing Zhang   +11 more
wiley   +1 more source

On the Epidemiology of Xenoma-Forming Microsporidia in Wild Caught Fish from Macaronesia (FAO34)

Veterinary Sciences
Microsporidia are a group of obligate intracellular parasites with a broad host range. These parasites can cause mild to severe harm to their hosts, making them important targets for research. However, studies on common wild-caught fish from the Atlantic
Kevin M. Santana-Hernández, Eva Betancor, Ana S. Ramírez, Begoña Acosta, Miriam Rodríguez, Emilio Soler-Onís, José Pestano, Eligia Rodríguez-Ponce   +7 more
doaj   +1 more source

Fish AI: Sustainable Commercial Fishing Challenge

, 2022
FishAI: Sustainable Commercial Fishingis the second chal-lenge at theNordic AI Meetfollowing the successful MedAI,which had a focus on medical image segmentation and trans-parency in machine learning (ML)-based systems. FishAI fo-cuses on a new domain, namely, commercial fishing and howto make it more sustainable with the help of machine learning.A ...
Nordmo, Tor-Arne Schmidt, Kvalsvik, Ove, Kvalsund, Svein Ove, Hansen, Birte, Halvorsen, Pål, Hicks, Steven, Johansen, Dag, Johansen, Håvard D., Riegler, Michael Alexander   +8 more
openaire   +1 more source

Five‐Year Disease Progression in Synuclein Seeding Positive Sporadic Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To provide a comprehensive description of disease progression in synuclein seeding assay (SAA) positive sporadic Parkinson Disease participants, using Neuronal Synuclein Disease integrated biological and functional impairment staging framework.
Paulina Gonzalez‐Latapi, Caroline Gochanour, Seung Ho Choi, Hyunkeun Cho, Chelsea Caspell‐Garcia, Christopher Coffey, Michael Brumm, David‐Erick Lafontant, Yuge Xiao, Thomas Tropea, John Seibyl, Caroline Tanner, Charles S. Venuto, Karl Kieburtz, Lana M. Chahine, Kathleen L. Poston, Andrew Siderowf, Kenneth Marek, Tanya Simuni, The Parkinson's Progression Markers Initiative   +19 more
wiley   +1 more source

Developmental and Epileptic Encephalopathy due to Biallelic Pathogenic Variants in PIGM

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective PIGM encodes a critical enzyme in the glycosylphosphatidylinositol (GPI)‐anchor biosynthesis pathway. While promoter‐region mutations in PIGM have been associated with a relatively mild phenotype characterized by portal vein thrombosis and absence seizures, recent evidence suggests that coding‐region mutations result in a more severe
Júlia Sala‐Coromina, Anna Marcé‐Grau, Barbara Masotto, Marta Codina, Lamia BenJemaa, Yasmina Elaribi, Mónica Martinez‐Gallo, Roger Colobran, Angel Sanchez‐Montañez, Irene Valenzuela, Yoshiko Murakami, Alfons Macaya   +11 more
wiley   +1 more source

Commercial Fish Oil

, 2021
Ham ticari balık yağı gaz-likit kromatografısi ile kalitatif ve kantitatif olarak analiz edildi. Saptanan başlıca yağ asidieri %24.8 stearik, %9.84 palmitik, %6.56 miristik, %6.56 oktadekatetraenoik asidlerdir. Ham ticari balık yağının fiziksel ve kimyasal özellikleri incelenmiş , bazı koku giderme metodları uygulanmış ve sonuçlar tartışılmıştır.
openaire   +1 more source

Marine heatwaves and commercial fishing in New Zealand

Science of The Total Environment
A marine heatwave (MHW) is an atypical and relatively short period of warmer Sea Surface Temperature (SST) which may be disruptive to marine life. Changes brought about by MHWs can reshape marine ecosystems in ways that have an economic impact on their users.
Miloud, Lacheheb, Ilan, Noy, Viktoria, Kahui   +2 more
openaire   +2 more sources