Results 91 to 100 of about 2,330,129 (358)
THE PROTECTION OF PERSONAL DATA - AN ESSENTIAL COMPONENT OF THE FUNDAMENTAL HUMAN RIGHTS [PDF]
Challenges of the Knowledge Society, 2019 In terms of human rights in general, and their promotion and protection, especially, developments have been and will continue to remain diverse and complex. This aspect addresses equally the concerns about the identification of human rights, as well as
Augustin FUEREA
doaj
Still the Committee of ‘Legislative Regions’? On Heterogeneity, Representation and Functionality of the Committee of the Regions after 2004 [PDF]
SSRN Electronic Journal, 2013 This article attempts to draw the picture of the Committee of the Regions after Treaty of Lisbon and the 2004 and 2007 enlargements of the European Union. The Committee of the Regions has received several new legal tools to influence EU decision taking, such as an increase in mandatory consultation rights and for the first time locus standi before the ...
openaire +2 more sources
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
Disparities between Development Regions and District Development Committees in Nepal [PDF]
, 2014 Julien Vandernoot, Camille Van Hove
openalex +1 more source
Molecular Oncology, EarlyView.EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain +10 more
wiley +1 more source
Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
Is There a Tomorrow for the Economic and Social Committee (EESC) and the Committee of the Regions (CoR)? [PDF]
, 2016 The main purpose of the two Committees is to engage participation from citizens in order to ensure that EU laws are geared to economic, social and regional conditions.
Duić, Dunja, Petrašević, Tunjica
core
Molecular Oncology, EarlyView.Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source
Estrogen and Progesterone Measurement and its Quality Control in Breast Cancer: A Reappraisal
The International Journal of Biological Markers, 1986 This article illustrates the two main methods for routine measurement of cytoplasmic estrogen receptor status in neoplastic biopsy. The first is the Dextran Coated Charcoal Technique (D.C.C.
Adriano Piffanelli +3 more
doaj +1 more source