Results 121 to 130 of about 14,377,340 (306)

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

Molecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq, Marc Terrones, Felicia Rodrigues Fortes, Anne Schepers, Alessia Denis, Christophe Deben, Ken Op de Beeck, Guy Van Camp, Geert Vandeweyer   +8 more
wiley   +1 more source

Common-Mode Voltage Mitigation by Novel Integrated Chokes and Modulation Techniques in Power Converter Systems

, 2013
Common-Mode Voltage Mitigation By Novel Integrated Chokes And Modulation Techniques In Power Converter ...
Ning Zhu (316672)
core   +1 more source

Current Harmonics Suppression of Six-Phase Permanent-Magnet Synchronous Motor Drives Using Back-Electromotive Force Harmonics Compensation

Energies
This paper investigates a back-electromotive force (EMF) harmonic compensation strategy for six-phase permanent-magnet synchronous motors (PMSMs) to reduce current harmonics and improve system performance.
Po-Sheng Huang, Cheng-Ting Tsai, Jonq-Chin Hwang, Cheng-Tsung Lin, Yu-Ting Lin   +4 more
doaj   +1 more source

Cancer‐associated mutations in endometriosis reframe a benign disease through molecular oncology

Molecular Oncology, EarlyView.
This review aims to comprehensively analyse cancer‐associated somatic mutations (CAMs) present in endometriotic lesions, emphasizing their biological roles, spatial distribution and implications for translational applications in medicine. By contextualizing a benign state within a genomic framework, this analysis seeks to establish its value as a ...
Clarissa Mujacic, Maria Concetta Vitale, Rita Siino, Emilia Di Giovanni, Carla Ferrante Bannera, Enrico Di Marco, Andrea Gottardo, Tancredi Didier Bazan Russo, Nadia Barraco, Alessandro Perez, Valerio Gristina, Antonio Galvano, Giuseppe Badalamenti, Antonio Russo, Viviana Bazan, Lorena Incorvaia   +15 more
wiley   +1 more source

Common-mode Voltage Reduction in a Motor Drive System with a Power Factor Correction

, 2012
Common-mode voltage generated by a power converter in combination with parasitic capacitive couplings is a potential source of shaft voltage in an AC motor drive system.
Ghosh, A., Adabi Firouzjaee, Jafar, Abbasalizadeh Boora, Arash, Adabi, J., Zare, F., Nami, A., Nami, Alireza, Ghosh, Arindam, Zare, Firuz, Blaabjerg, Frede, Blaabjerg, Frede; id_orcid, Boora, A.A.   +11 more
core   +1 more source

Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer

Molecular Oncology, EarlyView.
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim, Maryam Aslam, Elouise Torruella, Alphons Sony, Asif Rahman, Simira Smith, Columba de la Parra, Moira Sauane   +7 more
wiley   +1 more source

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

Molecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic, Rafael Stroggilos, Mladen Marinkovic, Ana Djuric, Suzana Stojanovic‐Rundic, Radmila Jankovic, Sergi Castellvi‐Bel, Remond J.A. Fijneman, Antonia Vlahou, Jerome Zoidakis, Milena Cavic   +10 more
wiley   +1 more source

Differential and common-mode filters based on metamaterial resonators [PDF]

, 2013
Two different techniques based on metamaterials for mitigating both the differential and common-mode propagation in differential signaling are addressed.
Gil Galí, Ignacio, Fernández García, Raúl   +1 more
core  

Dual-Tuned Removable Common-Mode Current Trap for Magnetic Resonance Imaging and Spectroscopy^. [PDF]

Annu Int Conf IEEE Eng Med Biol Soc, 2019
Enriquez AG, Vincent JM, Rispoli JV.
europepmc   +1 more source

Common-Mode Choke Design to Eliminate Electrostatic Discharge Machining Bearing Currents in Wide-Bandgap Inverter-Fed Motor Drives

Energies
The electrification of mobility sectors, including automotive, aerospace, and robotics, has accelerated the need for compact and high-efficiency power converters in electric motor drives. Wide-bandgap (WBG) semiconductor–based inverters offer significant
Mustafa Memon, Mohamed Diab
doaj   +1 more source