Results 41 to 50 of about 474,414 (304)

Quantum frequency goniometer with common mode noise cancellation

Optics Express
Small-angle measurement technology plays an important role in aerospace, lithography machine chip manufacturing, precision mechanical manufacturing, etc. However, despite decades of development, existing methods still rely on laser interferometers, and the resolution remains at 0.001 arcseconds.
Pengyuan Chang, Yuxuan Li, Haoran Zhong, Xiaolei Guan, Qiaohui Yang, Zhiyang Wang, Duo Pan, Jingbiao Chen   +7 more
openaire   +2 more sources

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

Near-Field Coupling Communication Technology For Human-Area Networking [PDF]

Journal of Systemics, Cybernetics and Informatics, 2012
We propose a human-area networking technology that uses the surface of the human body as a data transmission path and uses near-field coupling TRXs. This technology aims to achieve a "touch and connect" form of communication and a new concept of "touch ...
Ryoji Nagai, Taku Kobase, Tatsuya Kusunoki, Hitoshi Shimasaki, Yuichi Kado, Mitsuru Shinagawa   +5 more
doaj  

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

Modeling and Analysis of Conducted EMI in a Simulated Electric Vehicle Powertrain [PDF]

E3S Web of Conferences
This study describes an extensive simulation-based investigation of the conducted electromagnetic interference (EMI) using a complete EV powertrain system.
P Muthumari, S Bhuvaneswari
doaj   +1 more source

Inductorless Multi-Mode RF-CMOS Low Noise Amplifier Dedicated to Ultra Low Power Applications

IEEE Access, 2021
This work presents and analyses the design of a multi-mode Low Noise Amplifier (LNA) dedicated to 2.4 GHz Wireless Sensor Network (WSN) applications. The proposed inductorless LNA, implemented in a 28 nm FDSOI CMOS technology, is based on a common-gate ...
Thierry Taris, Jennifer Desevedavy, Frederic Hameau, Patrick Audebert, Dominique Morche   +4 more
doaj   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

Molecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Balanced Microwave Transmission Lines, Circuits, and Sensors

IEEE Journal of Microwaves, 2023
This paper provides an overview of balanced (or differential-mode) structures operating at microwaves, including common-mode suppression filters, balanced filters and circuits with intrinsic common-mode suppression, and differential-mode sensors.
Ferran Martin, Francisco Medina
doaj   +1 more source