Results 131 to 140 of about 482,540 (308)

Thermal runaway-induced short-circuit arc in highly integrated lithium-ion battery systems: mechanisms, thresholds, and mitigation strategies. [PDF]

Commun Eng
Yu Z, Chen C, Zhao P, Qiao Y, Cao Y, He B, Liu Z.   +6 more
europepmc   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source

Design and Characterization of a Prototype Pixel Readout Chip for Synchrotron Single Photon-Counting Detectors with 50 µm Pitch and 20 e^-rms ENC Noise. [PDF]

Sensors (Basel)
Lu S, Jiang Y, Sun T, Gan F, Wang T, Sheng Z.   +5 more
europepmc   +1 more source

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

Molecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi, Mandy Berndt‐Paetz, Eileen Lerner, Gregoire Najjar, Anca Azoitei, Krishna Pal Singh, Shailendra Kumar Gupta, Olaf Wolkenhauer, Cagatay Günes, Otmar Huber, Marc‐Oliver Grimm, Daniel Steinbach   +11 more
wiley   +1 more source

Modified design TWCI-based high step-up DC-DC converter with reduced elements and low input current ripple for renewable applications. [PDF]

Sci Rep
Tehranidoost Tabrizi MH, Sabahi M, Bannae Sharifian MB, Babaei E.   +3 more
europepmc   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

An Arduino-Based, Portable Prototype for the Recording and Analysis of EEG Signals to Support Self-Detection and Self-Monitoring of Stress. [PDF]

Sensors (Basel)
Baltzis S, Pagiatakis G, Voudoukis N, Papadakis A, Dritsas L, Uzunidis D.   +5 more
europepmc   +1 more source

The importance of common mode currents in high-voltage substations

, 1997
We measured in a substation the common mode (CM) curronts through secondary cables at the entry of a kiosk or a control room. Parameters of interest are the waveshape, the maximum dlldt, the amplitude and the frequency content. With these parameters and the biown transfer impedance of the cables one can test the adequacy of E7~iC measures to protect ...
Laan, van der, P.C.T., Deursen, van, A.P.J.   +1 more
openaire   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

Electromagnetic interference safety margins of cardiac implantable electronic devices from electric vehicle charging stations. [PDF]

Europace
Vivarelli C, Ricci F, Burriesci G, D'Agostino S, Falsaperla R, Calcagnini G, Mattei E.   +6 more
europepmc   +1 more source