Results 211 to 220 of about 498,734 (308)

Localized thermal tuning in fused silica inductive vibrating ring gyroscopes. [PDF]

Microsyst Nanoeng
Wu K, Wang X, Li Q, Lu K, Wang M, Wang C, Wu X, Xiao D.   +7 more
europepmc   +1 more source

The cooperative regulation of miR‐221 by APE1 and AUF1 impacts p27Kip1 defining a miR signature relevant for cervical cancer

FEBS Open Bio, EarlyView.
A regulatory axis involving APE1, AUF1, and miR‐221 is proposed. Pri‐miR‐221 is processed by DROSHA and DICER to generate mature miR‐221, which targets p27Kip1 mRNA. APE1 and AUF1 compete for pre‐miR‐221 binding. Reduced APE1/AUF1 levels impair miR‐221 biogenesis, decrease p27Kip1 mRNA degradation, and promote cell cycle progression, chemoresistance ...
Matilde Clarissa Malfatti, Nicolò Gualandi, Gianluca Tell, Giulia Antoniali   +3 more
wiley   +1 more source

Ionic and adhesive triboelectric elastomer for normalizing charge polarity and density of contact electrification with general material. [PDF]

Sci Adv
Qin S, Wang X, Gong H, Li X, Meng Z, Zheng L, Li N, Wang ZL, Chen X.   +8 more
europepmc   +1 more source

Dapagliflozin prevents methylglyoxal‐induced retinal cell death in ARPE‐19 cells

FEBS Open Bio, EarlyView.
Diabetic macular oedema is a diabetes complication of the eye, which may lead to permanent blindness. ARPE‐19 are human retinal cells used to study retinal diseases and potential therapeutics. Methylglyoxal is a compound increased in uncontrolled diabetes due to elevated blood glucose.
Naina Trivedi, Zainab Quraishi, Shima Khezri Azizi Far, Madaleine Ward, Aidan Conway, Reem Abdulredha, Eman Mshari, Yousif A. Shamsaldeen   +7 more
wiley   +1 more source

A Highly Linear Analog-to-Spike Converter

Akbari M, Covi E.
europepmc   +1 more source

GUIDE FOR SAMPLING POWER AND POWER QUALITY MEASUREMENTS [PDF]

, 2019
Andrei Pokatilov, Antoaneta Yovcheva, Aristo Philominraj, Bruno Trinchera, Helge Malmbekk, Huseyin Cayci, Javier Diaz de Aguilar, Kristian Ellingsberg, Marko Berginc, Martin Sera, Oliver Power, Ozlem Yilmaz, Radoslava Hadzhistoykova, Soureche Soccalingame, Stanislav Maslan, Stefan Svensson, Tansu Kefeli, Tobias Bergsten, Vera Novakova Zachovalova, Yolanda Alvarez Sanmamed   +19 more
core  

C2α‐carbanion‐protonating glutamate discloses tradeoffs between substrate accommodation and reaction rate in actinobacterial 2‐hydroxyacyl‐CoA lyase

FEBS Open Bio, EarlyView.
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn, Barbara Seroka, Ryszard Lazny, Zenon Lotowski, Thore Rohwerder   +4 more
wiley   +1 more source

Enhanced sliding mode control for parallel-integrated boost converters in hybrid solar-wind systems. [PDF]

Sci Rep
Arunyuvaraj K, M VP, Aravind P.
europepmc   +1 more source

PARP inhibitors induce a senescence phenotype in non‐small cell lung carcinoma cell lines

FEBS Open Bio, EarlyView.
Talazoparib is the most potent inducer of senescence among different PARP1 inhibitors in human NSCLC cells. In the absence of PARP, no senescence phenotype was observed, demonstrating that PARP1 is necessary for the induction of senescence by this inhibitor.
Camille Huart, Manon Van den Abbeel, Christoph Schifflers, Karim Bouhjar, Andrea Scarmelotto, Alexis Khelfi, Anne‐Catherine Wera, Carine Michiels   +7 more
wiley   +1 more source

Robust speed control of permanent magnet synchronous motors using model predictive and sliding mode strategies. [PDF]

PLoS One
Meawad M, Ahmed AA, Abdelkader MI, Dessouky YG.   +3 more
europepmc   +1 more source