Results 41 to 50 of about 960,349 (306)

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

One size fits all? Designer-institutions: Lessons from two flawed attempts in Malawi

International Journal of the Commons, 2010
This article observes two examples of attempted institutional design in Malawi's central region, Kasungu. In both cases external development actors enter local communities, and establish infrastructure to exploit two common sources of water.
Tomas Moe Skjølsvold
doaj   +1 more source

Longitudinal assessment of an integrated approach to large-scale common-pool water resource management: a case study of Nebraska’s Platte River basin

Ecology and Society, 2022
The state of Nebraska, USA employs a localized, integrated approach to managing water resources to address escalating quantity challenges. Here, we assess differences between agricultural water users’ perceptions of water management in a water-stressed ...
Mark E Burbach, Weston M Eaton, Barbara Quimby, Christina Babbitt, Jodi L Delozier   +4 more
doaj   +1 more source

DNA methylation and expression of MAPRE3 affect overall survival of early‐stage non‐small cell lung cancer patients

Molecular Oncology, EarlyView.
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen, Jiancheng Cheng, Ruili Hou, Xiaoyuan Zheng, Li Su, Maria Moksnes Bjaanæs, Anna Karlsson, Maria Planck, Johan Staaf, Åslaug Helland, Manel Esteller, David C. Christiani, Feng Chen, Xiaofei Cao, Ruyang Zhang   +14 more
wiley   +1 more source

Implementation of pasture leasing rights for mobile pastoralists – a case study on institutional change during post-socialist reforms in Azerbaijan

International Journal of the Commons, 2015
Our study focuses on pasture reform in Azerbaijan within the context of transition and pasture reform in Central Asian and Caucasian countries. Despite the rapid emergence of individualised rights for pasture plots, which is an exceptional development in
Regina Neudert, Michael Ruehs, Volker Beckmann   +2 more
doaj   +1 more source

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

FEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho, Rebecca Schmitt, Aneesha Dasgupta, Alexandra Ducharme, Jason Doles   +4 more
wiley   +1 more source

Property Rights on a Cold War battlefield: managing broadcasting transmissions through the Iron Curtain

International Journal of the Commons, 2011
This paper analyses the international regime governing the use of broadcasting frequencies in the long and medium wave bands in Europe from 1950 until 1970.
Christian Henrich-Franke
doaj   +1 more source

Re‐Awakening Public Attention to the Silent Pandemic of Cancer Among Older Adults in Low‐ and Middle‐Income Countries

Aging and Cancer, EarlyView.
ABSTRACT As global populations age, cancer is increasingly becoming a leading cause of morbidity and mortality among older adults, particularly in low‐ and middle‐income countries (LMICs). Despite accounting for the majority of new cancer cases and deaths, older individuals remain underrepresented in cancer research, clinical guidelines, and health ...
Ibrahim Bidemi Abdullateef, Sunkanmi Folorunsho, Abdulazeez Opeyemi Abdulganiyu   +2 more
wiley   +1 more source

Poverty and the Environment: Exploring the Relationship between Household Incomes, Private Assets, and Natural Assets [PDF]

Using purpose-collected survey data from 537 households in 60 different villages of the Jhabua district of India, this paper investigates the extent to which rural households depend on common-pool natural resources for their daily livelihood.
Gupta, Shreekant, Narain, Urvashi, van 't Veld, Klaas   +2 more
core   +3 more sources

The role of institutions in community wildlife conservation in Zimbabwe

International Journal of the Commons, 2018
Institutions play a significant role in stabilizing large-scale cooperation in common pool resource management. Without restrictions to govern human behaviour, most natural resources are vulnerable to overexploitation.
Herbert Ntuli, Edwin Muchapondwa
doaj   +1 more source