Results 61 to 70 of about 9,416,735 (293)
GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma
FEBS Open Bio, EarlyView.GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain +11 more
wiley +1 more source
Effects of Threshold Uncertainty on Common-Pool Resources [PDF]
, 2014 Many natural resources and common-pool resources have inherent thresholds regarding the onset of deleterious environmental impacts or consequences. Group and individual behavior were examined in an experimental setting using three distinct games designed
Adler Mandelbaum, Sara E
core +8 more sources
Understanding large social-ecological systems: introducing the SESMAD project
International Journal of the Commons, 2014 This article introduces the Social-ecological systems meta-analysis database (SESMAD) project, which is the project behind the case studies and synthetic articles contained in this special issue of the 'International Journal of the Commons'. SESMAD is an
Michael Cox
doaj +1 more source
BCG vaccination potentiates oxidative phosphorylation in neonatal myeloid‐derived suppressor cells
FEBS Open Bio, EarlyView.BCG vaccination enhances oxidative phosphorylation in neonatal MDSCs, impairing their immunosuppressive function. It upregulates electron transport chain genes and mitochondrial activity, increasing ATP and oxygen consumption. Pharmacological OXPHOS inhibition partially restores suppressive capacity, confirming causality.
Yingying Chen, Hui Li
wiley +1 more source
Revue de Géographie Alpine, 2008 Common-pool resources are natural or man-made resources shared among different users, a condition that produces a competition for their utilization leading often (although not necessarily) to their degradation or even to their destruction.
Giangiacomo Bravo, Beatrice Marelli
doaj +1 more source
An Intergenerational Common Pool Resource Experiment [PDF]
intergenerational common pool resources;growth and altruism;free-riding ...
Irlenbusch, B. +2 more
core
MARK4 enhances stress granule formation under oxidative stress and increases tau accumulation
FEBS Open Bio, EarlyView.MARK4 (red dots) localizes to stress granules (orange dots) and promotes their formation under oxidative stress by modulating TIA1 (blue dots). MARK4 and TIA1 synergistically increase tau (purple) accumulation, and the reduction of the TIA1 ortholog suppresses neurodegeneration in a fly model.
Sho Nakajima +8 more
wiley +1 more source
Kenyan pastoralist societies in transition: varying perceptions of the value of ecosystem services
Ecology and Society, 2014 In the drylands of northern Kenya, as elsewhere in Africa, traditional pastoralist social-ecological systems are undergoing profound transformations.
Eva Kaye-Zwiebel, Elizabeth King
doaj +1 more source
The Role of Rivalry. Public Goods versus Common-Pool Resources [PDF]
Despite a large theoretical and empirical literature on public goods and common-pool resources, a systematic comparison of these two types of social dilemmas is lacking. In fact, there is considerable confusion about these two types of dilemma situations.
Jose Apesteguia, Frank P. Maier-Rigaud
core
Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level
Aging and Cancer, EarlyView.This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley +1 more source