Results 91 to 100 of about 5,236,906 (300)

Incidence of carotid artery stenosis in acute ischemic stroke at BMC Hospital Quetta [PDF]

open access: yesRomanian Journal of Neurology
Background and objectives. This study aimed to explore the prevalence, severity, and distribution of carotid artery stenosis among patients experiencing ischemic strokes. Materials and methods.
Muhammad Essa   +10 more
doaj   +1 more source

Targeted Degradation of STING by a Neutrophil Membrane‐Coated Nanoplatform Suppresses Microglial Pyroptosis After Subarachnoid Hemorrhage

open access: yesAdvanced Science, EarlyView.
MG1@NM‐Px serves as a microglia‐targeted STING‐degrading nanoplatform for subarachnoid hemorrhage. Following systemic administration, it crosses the blood–brain barrier and accumulates in activated microglia. STP1‐mediated STING ubiquitination and degradation suppress MAPK/inflammasome signaling, GSDME‐mediated pyroptosis, and IL‐1β release, revealing ...
Ruotian Zhang   +13 more
wiley   +1 more source

Spontaneous cervical artery dissection involving the common and internal carotid arteries associated with eosinophilic granulomatosis with polyangiitis: a case report

open access: yesThe Egyptian Journal of Neurology, Psychiatry and Neurosurgery
Background Eosinophilic granulomatosis with polyangiitis (EGPA) is a rare, multisystemic, immune-mediated inflammatory disease. Carotid artery dissections involving both the cervical internal carotid artery and common carotid artery are rare.
Hideki Endo   +2 more
doaj   +1 more source

An alternative surgical approach reduces variability following filament induction of experimental stroke in mice

open access: yesDisease Models & Mechanisms, 2017
Animal models are essential for understanding the pathology of stroke and investigating potential treatments. However, in vivo stroke models are associated, particularly in mice, with high variability in lesion volume.
Melissa Trotman-Lucas   +4 more
doaj   +1 more source

USP5 Stabilizes TGFBR1 to Drive Vascular Smooth Muscle Cell Senescence and Atherosclerosis

open access: yesAdvanced Science, EarlyView.
This study reveals that USP5 drives vascular smooth muscle cell senescence and atherosclerosis by stabilizing TGFBR1, suppressing IDH2, and promoting glycolytic reprogramming, identifying the USP5‐TGFBR1‐IDH2 axis as a potential therapeutic target. ABSTRACT Vascular smooth muscle cell (VSMC) senescence contributes importantly to atherosclerotic plaque ...
Xinhai Cui   +5 more
wiley   +1 more source

Analysis of the Common Carotid Arterial System in the Electrical Circuit Based on the Three-element Model:Effects of Neck Retrocollis

open access: yes, 2016
This study investigated the physical properties of the arterial system originating from the common carotid artery (hereinafter called the common carotid arterial system) during retrocollis of the head by assuming the arterial system to the electrical ...
34, OKAMURA, Noritaka
core   +1 more source

Ultrasound IMT measurement on a multi-ethnic and multi-institutional database: Our review and experience using four fully automated and one semi-automated methods [PDF]

open access: yes, 2012
Automated and high performance carotid intima-media thickness (IMT) measurement is gaining increasing importance in clinical practice to assess the cardiovascular risk of patients. In this paper, we compare four fully automated IMT measurement techniques
Jasjit, S.   +27 more
core   +1 more source

Copper‐Doped Prussian Blue Nanozymes With Hyaluronic Acid‐Mediated Targeting Alleviate Oxidative Stress and Regulate Cholesterol Handling for Atherosclerosis Therapy

open access: yesAdvanced Science, EarlyView.
CuPB@HA is a CD44‐associated, plaque‐targeted nanozyme that alleviates oxidative stress, inflammation, and lipid accumulation in macrophages. By reducing CD36‐dependent lipid uptake and promoting ABCA1/ABCG1‐mediated cholesterol handling, it improves macrophage function, preferentially accumulates in atherosclerotic lesions, reduces plaque burden, and ...
Jianliang Ou   +14 more
wiley   +1 more source

Carotid reconstruction under specific clinical conditions: unilateral carotid stenosis, contralateral carotid occlusion, bilateral carotid stenosis, and concomitant coronary artery disease

open access: yes, 2023
Stroke has an immense burden on public health not only due to its high mortality but also because many of the survivors are left with a lifelong disability decreasing their quality of life.
Mathews, Robin Roy
core  

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