Results 71 to 80 of about 143,528 (308)

Selective Inhibition of Integrin β3 Topology Provides a Safer Antithrombotic Strategy

open access: yesAdvanced Science, EarlyView.
Current integrin αIIbβ3 inhibitors effectively reduce thrombosis but also increase bleeding risk. During thrombosis, high shear blood flow can directly activate the integrin αIIbβ3 via a distinct topological change in the β3 transmembrane domain, independent of hemostatic platelet signaling.
Joonha Lee   +11 more
wiley   +1 more source

Analysis of the Common Carotid Arterial System in the Electrical Circuit Based on the Three-element Model:Effects of Neck Retrocollis

open access: yes, 2016
This study investigated the physical properties of the arterial system originating from the common carotid artery (hereinafter called the common carotid arterial system) during retrocollis of the head by assuming the arterial system to the electrical ...
34, OKAMURA, Noritaka
core   +1 more source

S100A14 in Tumor‐Derived EVs Targets PIAS3 to Reprogram Astrocytes and Induce Immunosuppressive Microenvironment Promoting Brain Metastasis and Germacrone Reversal Effect

open access: yesAdvanced Science, EarlyView.
This study identifies S100A14 in tumor‐derived exosomes as a key driver of brain metastasis. S100A14 targets PIAS3 in astrocytes, activating STAT3 signaling and promoting immunosuppressive MDSCs recruitment via chemokine secretion. Germacrone, a natural compound, binds S100A14 to disrupt this axis, effectively inhibiting brain metastasis with low ...
Qian Feng   +13 more
wiley   +1 more source

Carotid artery stenting via a femoral bypass graft: technical note. [PDF]

open access: yes, 2008
BACKGROUND: We described a case of endoluminal stent placement for a cervical internal carotid artery stenosis in which access was obtained via the femoral bypass graft.
Nagata, Izumi   +7 more
core   +1 more source

A Crack‐Based One‐Dimensional Microspheres Array Enables Thermal–Mechanical Decoupled Dual‐Functional Sensing

open access: yesAdvanced Science, EarlyView.
Inspired by Nostoc, a crack‐based one‐dimensional microspheres array (COMA) sensor is developed, which stabilizes crack geometry under isotropic expansion, enabling a predictable, monotonic thermal response from which true strain can be accurately extracted. The COMA sensor exhibits high sensitivity at ultralow deformation (gauge factor up to 89) and a
Wanqing Xu   +7 more
wiley   +1 more source

Menopausal Status and Distensibility of the Common Carotid Artery [PDF]

open access: yesArteriosclerosis, Thrombosis, and Vascular Biology, 1999
Abstract —Although several studies have shown that exogenous estrogens have beneficial effects on arterial characteristics, the effect of endogenous estrogen on the vascular system is still unknown. In this study, distensibility, an indicator of arterial elasticity, of the common carotid artery was compared in pre- and ...
Westendorp, I.C.D.   +7 more
openaire   +4 more sources

Topologically Structured PLLA Fibers With Stress Concentration Effects for Health Monitoring

open access: yesAdvanced Science, EarlyView.
In this study, a multi‐path strategy was developed to enhance the piezoelectric properties of PLLA fibers through the stress concentration effect. The optimized devices generate piezoelectric output up to 14 times that of pure PLLA fibers. This piezoelectric enhancement strategy offers a new approach for high‐performance piezoelectric devices, with ...
Longfei Li   +8 more
wiley   +1 more source

An alternative surgical approach reduces variability following filament induction of experimental stroke in mice

open access: yesDisease Models & Mechanisms, 2017
Animal models are essential for understanding the pathology of stroke and investigating potential treatments. However, in vivo stroke models are associated, particularly in mice, with high variability in lesion volume.
Melissa Trotman-Lucas   +4 more
doaj   +1 more source

Differences in Carotid Artery Geometry and Flow Caused by Body Postural Changes and Physical Exercise

open access: yes, 2023
Different body postures and physical exercises may lead to changes in arterial geometry and hemodynamics, which may be associated with the distribution of atherosclerosis lesions.
Zhiyong Li   +17 more
core   +1 more source

Home - About - Disclaimer - Privacy