Results 91 to 100 of about 200,357 (255)

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

FEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

Existence and Unique Coupled Solution in S_b-Metric Spaces by Rational Contraction with Application

Mathematics, 2019
In this paper, we prove a unique common coupled fixed point theorem for two pairs of w-compatible mappings in S b -metric spaces. We also furnish an example to support our main result.
Jelena Vujaković, Gajula Naveen Venkata Kishore, Konduru Pandu Ranga Rao, Stojan Radenović, Shaik Sadik   +4 more
doaj   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

FEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas, Brigitta Maruzs, Zsófia E. Kálmán, Tomas Klumpler, Gyula Batta, Bálint Péterfia, Zoltán Gáspári   +6 more
wiley   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

FEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee, Junho Jeong, Chae Yeong Lee, Hyunjoon Cho, Man Hwan Oh, Je Chul Lee, Jee‐Young Lee, Yangmee Kim   +7 more
wiley   +1 more source

Coupled Coincidence and Coupled Common Fixed Points of (ψ, ϕ) Contraction Type T-coupling in Metric Spaces

Iranian Journal of Mathematical Sciences and Informatics
Summary: In this paper, we define \((\psi, \phi)\)-contraction Type \(T\)-coupling, establish a theorem satisfying such contraction condition, and prove the existence and uniqueness of coupled coincidence and coupled common fixed points in metric space.
Abdulkerim, Fuad, Koyas, Kidane, Gebregiorgis, Solomon   +2 more
openaire   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

FEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Coupled Coincidence Point Theorems for Nonlinear Contractions in Partially Ordered Quasi-Metric Spaces with a Q-Function

Fixed Point Theory and Applications, 2011
Using the concept of a mixed g-monotone mapping, we prove some coupled coincidence and coupled common fixed point theorems for nonlinear contractive mappings in partially ordered complete quasi-metric spaces with a Q-function q.
Shah MH, Hussain N, Kutbi MA
doaj  

Application of Coupled Fixed Point Technique in Solving Integral Equations on Modified Intuitionistic Fuzzy Metric Spaces

Advances in Fuzzy Systems, 2014
We establish a common coupled fixed point theorem for weakly compatible mappings on modified intuitionistic fuzzy metric spaces. As an application of our result, we study the existence and uniqueness of the solution to a nonlinear Fredholm integral ...
Bhavana Deshpande, Amrish Handa
doaj   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

FEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar, Xinqi Yan, Lucas F. Jansen Klomp, Stefano Schivo, Janine N. Post   +4 more
wiley   +1 more source