Results 71 to 80 of about 2,578,328 (266)

Development and implementation of common data elements for venous thromboembolism research: on behalf of SSC Subcommittee on official Communication from the SSC of the ISTH

Journal of Thrombosis and Haemostasis, 2020
Clinical research in venous thromboembolism (VTE) is hindered by variability in the collection and reporting of data and outcomes. A consistent data language facilitates efficiencies, leads to higher quality data, and permits between‐study comparisons ...
G. Le Gal, M. Carrier, L. Castellucci, A. Cuker, J. Hansen, F. Klok, N. Langlois, J. Levy, S. Middeldorp, M. Righini, Sam Walters   +10 more
semanticscholar   +1 more source

Dendritic cells steering antigen and leukocyte traffic in lymph nodes

FEBS Letters, EarlyView.
Dendritic cells are key players in the activation of T cells and their commitment to effector function. In this In a Nutshell Review, we will discuss how dendritic cells guide the trafficking of antigen and leukocytes in the lymph node, thus influencing T‐cell activation processes. Dendritic cells (DCs) play a central role in initiating and shaping the
Enrico Dotta, Agnieszka Katarzyna Maciola, Tania Baccega, Giulia Pasqual   +3 more
wiley   +1 more source

Unleashing the value of Common Data Elements through the CEDAR Workbench

AMIA ... Annual Symposium proceedings. AMIA Symposium, 2019
Developing promising treatments in biomedicine often requires aggregation and analysis of data from disparate sources across the healthcare and research spectrum. To facilitate these approaches, there is a growing focus on supporting interoperation of datasets by standardizing data-capture and reporting requirements. Common Data Elements (CDEs)—precise
Martin J, O'Connor, Denise B, Warzel, Marcos, Martínez-Romero, Josef, Hardi, Debra, Willrett, Attila L, Egyedi, Aras, Eftekhari, John, Graybeal, Mark A, Musen   +8 more
openaire   +3 more sources

Development of Common Data Elements to Provide Tele self-Care Management [PDF]

Acta Informatica Medica, 2013
Self-care management could empower patients to management of their health. Tele-health is the remote exchange of data between a patient and medical staff to improve healthcare quality.The aim of this research was developing common data elements to provide Tele self-care management and improve quality of care.This was a cross-sectional study based on ...
Fatemeh Rangraz Jeddi, Mohammad Reza Rezaiimofrad   +1 more
openaire   +3 more sources

Moving Towards Common Data Elements and Core Outcome Measures in Frailty Research [PDF]

The Journal of Frailty & Aging, 2020
With aging populations around the world, frailty is becoming more prevalent increasing the need for health systems and social systems to deliver optimal evidence based care. However, in spite of the growing number of frailty publications, high-quality evidence for decision making is often lacking.
Muscedere, J., Afilalo, J., Araujo de Carvalho, I., Cesari, M., Clegg, A., Eriksen, H. E., Evans, K. R., Heckman, G., Hirdes, J. P., Kim, P. M., Laffon, B., Lynn, J., Martin, F., Prorok, J. C., Rockwood, K., Rodrigues Mañas, L., Rolfson, D., Shaw, G., Shea, B., Sinha, S., Theou, O., Tugwell, P., Valdiglesias, V., Vellas, B., Veronese, N., Wallace, L. M. K., Williamson, P. R.   +26 more
openaire   +3 more sources

The dual nature of TDC – bridging dendritic and T cells in immunity

FEBS Letters, EarlyView.
TDC are hematopoietic cells combining dendritic and T cell features. They reach secondary lymphoid organs (SLOs) and peripheral organs (liver and lungs) after FLT3‐dependent development in the bone marrow and maturation in the thymus. TDC are activated and enriched in SLOs upon viral infection, suggesting that they might play unique immune roles, since
Maria Nelli, Mirela Kuka
wiley   +1 more source

Optimising Clinical Epidemiology in Disease Outbreaks: Analysis of ISARIC-WHO COVID-19 Case Report Form Utilisation

Epidemiologia
Standardised forms for capturing clinical data promote consistency in data collection and analysis across research sites, enabling faster, higher-quality evidence generation. ISARIC and the World Health Organization have developed case report forms (CRFs)
Laura Merson, Sara Duque, Esteban Garcia-Gallo, Trokon Omarley Yeabah, Jamie Rylance, Janet Diaz, Antoine Flahault, ISARIC Clinical Characterisation Group   +7 more
doaj   +1 more source

Common data elements collected among universities for sport-related concussion studies

Injury Epidemiology, 2018
Background Universities are increasingly implementing programs to effectively respond to and manage sport-related concussions (SRCs). One such effort is to develop common data elements (CDEs) and standardize data collection methods.
Jingzhen Yang, Corinne Peek-Asa, James M. Noble, James Torner, Paul Schmidt, Martha L. Cooper, Big Ten – Ivy League Traumatic Brain Injury Research Collaboration Data Collection Working Group   +6 more
doaj   +1 more source

Improving the value of clinical research through the use of Common Data Elements [PDF]

Clinical Trials, 2016
The use of Common Data Elements can facilitate cross-study comparisons, data aggregation, and meta-analyses; simplify training and operations; improve overall efficiency; promote interoperability between different systems; and improve the quality of data collection.
Joanne Odenkirchen, Lisa Lang, Ellen M. Werner, Yaffa R. Rubinstein, Steven Hirschfeld, Erin D. Foster, Michael F. Huerta, Udi E. Ghitza, Dianne Reeves, Joanna Karpinski, Kerry Goetz, Jerry Sheehan, Richard P. Moser   +12 more
openaire   +2 more sources

Leveraging current insights on IL‐10‐producing dendritic cells for developing effective immunotherapeutic approaches

FEBS Letters, EarlyView.
In vivo IL‐10 produced by tissue‐resident tolDC is involved in maintaining/inducing tolerance. Depending on the agent used for ex vivo tolDC generation, cells acquire common features but prime T cells towards anergy, FOXP3+ Tregs, or Tr1 cells according to the levels of IL‐10 produced. Ex vivo‐induced tolDC were administered to patients to re‐establish/
Konstantina Morali, Gloria Giacomello, Michela Vuono, Silvia Gregori   +3 more
wiley   +1 more source