Results 61 to 70 of about 17,485,358 (248)

Smaller is better: nanobodies meet NMR

open access: yesFEBS Letters, EarlyView.
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley   +1 more source

A Column Generation Algorithm For Common Due Date Scheduling [PDF]

open access: yes, 1996
We consider the single-machine problem of scheduling n jobs to minimize the total weighted deviation from a given common due date, where the weights for early and tardy completion are asymmetric. First, we assume that the common due date is large.
van den Akker, J.M.   +10 more
core  

Cancer‐associated mutations in endometriosis reframe a benign disease through molecular oncology

open access: yesMolecular Oncology, EarlyView.
This review aims to comprehensively analyse cancer‐associated somatic mutations (CAMs) present in endometriotic lesions, emphasizing their biological roles, spatial distribution and implications for translational applications in medicine. By contextualizing a benign state within a genomic framework, this analysis seeks to establish its value as a ...
Clarissa Mujacic   +15 more
wiley   +1 more source

Multiple recurrences in Pityriasis rosea - A case report with review of the literature

open access: yesIndian Journal of Dermatology, 2014
Pityriasis rosea (PR) is a common benign cutaneous disorder of children and young adults. The etiology of this condition is still unknown. Despite the common occurrence, second episode of PR is noted only in 1-3% of the cases. Multiple recurrences (three
Senthilkumar Sankararaman   +1 more
doaj   +1 more source

Spatial biology in cancer epigenetics

open access: yesMolecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

Epidermal Growth Factor Receptor Inhibitors: A Review of Cutaneous Adverse Events and Management

open access: yesDermatology Research and Practice, 2014
Epidermal growth factor inhibitors (EGFRI), the first targeted cancer therapy, are currently an essential treatment for many advance-stage epithelial cancers.
K. Chanprapaph   +2 more
doaj   +1 more source

Vermicompost Supply Modifies Chemical Composition and Improves Nutritive and Medicinal Properties of Date Palm Fruits From Saudi Arabia

open access: yesFrontiers in Plant Science, 2019
To meet the increased demand for phytochemicals, plant cultivation in soil amended with biofertilizers has been developed. Here, we aimed to use vermicompost as an environmentally safe biofertilizer to enhance the nutritive and medicinal value of five ...
Soad Al Jaouni   +11 more
doaj   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

open access: yesMolecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi   +6 more
wiley   +1 more source

Permutation Flowshop Scheduling with Earliness and Tardiness Penalties [PDF]

open access: yes
We address the permutation flowshop scheduling problem with earliness and tardiness penalties (E/T) and common due date of jobs. Large number of process and discrete parts industries follow flowshop type of production process.
Peeyush Mehta   +2 more
core  

Integrated Process Planning, Scheduling, and Due-Date Assignment

open access: yes
Traditionally, the three most important manufacturing functions are process planning, scheduling, and due-date assignment, which are handled sequentially and separately.This book integrates these manufacturing processes and functions to increase global ...

core   +1 more source

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